- Harvesting Mechanical Work From Folding|Based Protein Engines🔍
- Prashant K Purohit🔍
- Does protein unfolding play a functional role in vivo?🔍
- Influence of Hydroxyproline on Mechanical Behavior of Collagen ...🔍
- Acetic Acid Enables Precise Tailoring of the Mechanical Behavior of ...🔍
- Mechanical regulation of talin through binding and history ...🔍
- Mechanical Unfolding of a Я|Hairpin Using Molecular Dynamics🔍
- Mechanical unfolding of alpha| and beta|helical protein motifs🔍
Protein unfolding accounts for the unusual mechanical behavior of ...
Harvesting Mechanical Work From Folding-Based Protein Engines
Mechanochemical coupling cycles underlie the work-generation mechanisms of biological systems and are realized by highly regulated ...
Prashant K Purohit - Google Scholar
Protein unfolding accounts for the unusual mechanical behavior of fibrin networks. PK Purohit, RI Litvinov, AEX Brown, DE Discher, JW Weisel. Acta ...
Does protein unfolding play a functional role in vivo? - FEBS Press
This process represents a gain-of-function, as it allows unique responses that integrate mechanical signals with chemical interactions. Finally, ...
Influence of Hydroxyproline on Mechanical Behavior of Collagen ...
The SMD simulations emulate the fraying of each α-chain from the triple-helical, causing the deformation and unfolding of the collagen protein molecule as the ...
(PDF) Mechanism of Fibrin(ogen) Forced Unfolding - Academia.edu
Protein unfolding accounts for the unusual mechanical behavior of fibrin networks. Acta Biomater. 2011; 7:2374–2383. [PubMed: 21342665] Raman EP, Barsegov V ...
Acetic Acid Enables Precise Tailoring of the Mechanical Behavior of ...
... protein folding transitions on BSA-based hydrogel mechanical behavior. ... Protein-based hydrogels are unique biomaterials as they are ...
Mechanical regulation of talin through binding and history ... - Science
This history-dependent behavior indicates the evolution of a unique force-induced native state. We measure through mechanical unfolding that ...
ABSTRACT Single-molecule mechanical unfolding experiments have the potential to provide insights into the details of protein folding pathways.
Mechanical unfolding of alpha- and beta-helical protein motifs
... protein networks, where beta-helices offer unique properties. Original language, English (US). Pages (from-to), 1243-1252. Number of pages, 10. Journal, Soft ...
Mechanism of Fibrin(ogen) Forced Unfolding
unfolding is necessary to account for fibrin's unusual properties. ... Protein unfolding accounts for the unusual mechanical behavior of fibrin networks.
Investigating the folding-unfolding mechanisms of metalloproteins ...
... proteins and one heme-containing protein. First, we studied the mechanical unfolding behavior of a high potential iron-sulfur protein by atomic force ...
Publications — Behavioural Phenomics
Protein unfolding accounts for the unusual mechanical behavior of fibrin networks. Acta Biomaterialia 7:2374-2383. 2010. A Zemel*, F Rehfeldt*, AEX Brown, DE ...
To understand the mechanical functions of proteins, it is important to know the protein structure and mechanical properties. Protein mechanics ...
Thermal versus mechanical unfolding in a model protein
As protein folding is known to be a highly complex and multidimensional process, it is unlikely that the distance between the N-terminal and C-terminal of a ...
Mechanical transition from α-helical coiled coils to β-sheets in fibrin ...
... protein networks, where beta-helices offer unique properties. Expand ... Protein unfolding accounts for the unusual mechanical behavior of fibrin networks.
Protein folding is the physical process by which a protein, after synthesis by a ribosome as a linear chain of amino acids, changes from an unstable random ...
6, e16890, (2011). 25. “Protein unfolding accounts for the unusual mechanical behavior of fibrin networks” Prashant K. Purohit, Rustem I. Litvinov, Andre ...
Fold and flexibility: what can proteins' mechanical properties tell us ...
Our approach however leads to the determination of a unique consensus nucleus that coincides with the R15 repeat's folding nucleus. As a ...
β-sheet-like formation during the mechanical unfolding of prion protein
Single molecule experiments and simulations have been widely used to characterize the unfolding and folding pathways of different proteins.
Atomic force microscopy reveals the mechanical design of a ...
We constructed a heteropolyprotein by combining I27 and I28 domains in series and found two distinct levels of unfolding forces; we first observed the unfolding ...