Rafts and synapses in the spatial organization of immune cell ...

Assembly of the immunological synapse for T cells and NK cells

... immunological synapse and in T cell activation, Immunity, № 15, с. ... Dykstra, Rafts and synapses in the spatial organization of immune cell signaling receptors, ...

Impaired TCR signaling through dysfunction of lipid rafts in ...

They have been implicated in the cytoskeletal re-organization that forms platform immunological synapses at the cell membrane, which are ...

Full article: The “acrosomal synapse” - Taylor & Francis Online

26,Citation27 Since recent observations indicate that lipid rafts and a variety of scaffolding proteins are also present in sperm cells, we summarize new ...

Signaling Takes Shape in the Immune System - Cell Press

... system and immune systems on molecular organization of synapses are just beginning. ... T cell costimulation by enhancing the association of TCR with rafts.

Membrane rafts and signaling by the multichain immune recognition ...

... Rafts and synapses in the spatial organization of immune cell signaling receptors. Dykstra M, Cherukuri A, Pierce SK · J Leukoc Biol, 70(5):699-707, 01 Nov ...

The dendritic cell side of the immunological synapse - De Gruyter

Immune responses are initiated by the interactions between antigen-presenting cells (APCs), such as dendritic cells (DCs), with responder ...

Spatial organization of transmembrane receptor signalling

... raft hypothesis: lipid rafts play a role in immune cell activation. ... Groves JT (2006) Spatial mutation of the T cell immunological synapse. Curr ...

Untitled

... T Cell Biology, a section of the journal Frontiers in Immunology Received: 17 September 2015 Accepted: 18 December 2015 Published: 11 January 2016 Citation ...

NK cell survival mediated through the regulatory synapse with ... - JCI

Spatial organization of signal transduction ... Early liaisons between cells of the innate immune system in inflamed peripheral tissues.

Analysis of detergent-free lipid rafts isolated from CD4+ T cell line

More so, how the spatial distribution of signaling molecules relates to temporal signaling is unknown. However, recently, re-organization on the ...

Galectin-3 modulation of T-cell activation: mechanisms of ... - HAL

Primarily, Gal3 supresses T cell activation. 426 by altering the spatial organization of the immune synapses. At physiological levels, this. 427 suppression ...

Exclusion of Lipid Rafts and Decreased Mobility of CD94/NKG2A ...

Signaling at the inhibitory natural killer cell immune synapse regulates lipid raft polarization but not class I MHC clustering. Proc. Natl. Acad. Sci. USA ...

The integration of signaling and the spatial organization of the T cell ...

recently examined the patterns of immunologi- cal synapses in self-reactive T cells clonally derived from patients. Frontiers in Immunology | ...

A guide to cancer immunotherapy: from T cell basic science ... - Nature

This provided unequivocal evidence that the immune system, in particular T cells (see Box 1 and Fig. ... Spatial organization as a regulatory ...

The integration of signaling and the spatial organization of the T cell ...

recently examined the patterns of immunologi- cal synapses in self-reactive T cells clonally derived from patients. Frontiers in Immunology | ...

Control of Immune Responses by Trafficking Cell Surface Proteins ...

Thus, we also present here a critical discussion of the technologies used to study lipid rafts and, more broadly, a map of the spatial and ...

Macrophage activation on “phagocytic synapse” arrays: Spacing of ...

... immune responses by engineering the spatial organization of cell receptors. Recent studies have shown potential applications of Pam3 (61) ...

The integration of signaling and the spatial organization of the T cell ...

The integration of signaling and the spatial organization of the T cell synapse. Frontiers in Immunology. November 2012; 3:352. DOI ...

Lipid rafts and neurodegeneration: structural and functional roles in ...

Neural lipid rafts are found in brain cells, including neurons, astrocytes, and microglia, and are characterized by a high enrichment of specific lipids ...

Impaired TCR signaling through dysfunction of lipid rafts in ...

They have been implicated in the cytoskeletal re-organization that forms platform immunological synapses at the cell membrane, which are involved in signal ...