Review Clinical and genetic issues in dilated cardiomyopathy

Clinical and genetic issues in familial dilated cardiomyopathy

Idiopathic dilated cardiomyopathy (IDC) is characterized by left ventricular dilatation and systolic dysfunction after known causes have been excluded.

Genetics of Adult-Onset Dilated Cardiomyopathy

The following are key points to remember from this state-of-the-art review on the genetics of adult-onset dilated cardiomyopathy (DCM).

Evidence-Based Assessment of Genes in Dilated Cardiomyopathy

Background: Each of the cardiomyopathies, classically categorized as hypertrophic cardiomyopathy, dilated cardiomyopathy (DCM), and arrhythmogenic right ...

Genetics of Dilated Cardiomyopathy - Annual Reviews

In addition to standard treatment of heart failure and prevention of arrhythmias and sudden cardiac death, patients with genetic cardiomyopathy ...

Clinical and genetic issues in familial dilated cardiomyopathy

A consensus has emerged that with a new diagnosis of idiopathic dilated cardiomyopathy (IDC), the clinical screening of first-degree family ...

Dilated cardiomyopathy in the era of precision medicine

Cardiac manifestations may be expressed in the form of restrictive cardiomyopathy, DCM, conduction system disorders, Vas, or SCD [61].

Understanding the genetics of adult-onset dilated cardiomyopathy

cardiomyopathy, dilated; genetics; genetic screening. Issue Section: State of the Art Review > Heart failure and cardiomyopathies.

Importance of Genetic Testing in Dilated Cardiomyopathy

Dilated cardiomyopathy (DCM) is a clinical syndrome characterized by left ventricular dilatation and contractile dysfunction. It is the most common cause of ...

Hereditary Dilated Cardiomyopathy: Recent Advances in Genetic ...

Dilated cardiomyopathy (DCM) is the most common cause of heart failure in young adults and up to 50% of idiopathic DCM is thought to be ...

Importance of Genetic Testing in Dilated Cardiomyopathy - SciELO

Dilated cardiomyopathy (DCM) is a clinical syndrome characterized by left ventricular dilatation and contractile dysfunction. It is the most common cause of ...

The Genetic Evaluation of Dilated Cardiomyopathy - Structural Heart

A genetic etiology can be found in 20-35% of patients with DCM, especially in those with a family history of cardiomyopathy or sudden cardiac death at an early ...

Genetic mutations and mechanisms in dilated cardiomyopathy - JCI

Cardiomyopathy is most commonly diagnosed through in vivo imaging, with either echocardiography or, increasingly, cardiac MRI. DCM refers to enlargement of the ...

Study shows benefit of routine genetic testing of dilated ...

Researchers found that DCM patients with advanced heart disease, defined as having a heart transplant or left ventricular assist device (LVAD), ...

Clinical Implications of the Genetic Architecture of Dilated ...

Dilated cardiomyopathy (DCM) frequently involves an underlying genetic etiology, but the clinical approach for genetic diagnosis and ...

Genetic Counseling and Screening Issues in Familial Dilated ...

KEY WORDS: dilated cardiomyopathy; genetic counseling; cardiac genetics. INTRODUCTION. Cardiomyopathy (“heart muscle disease”) is a common cause of heart ...

Genetics and genomics of dilated cardiomyopathy and systolic heart ...

One of the main causes of systolic heart failure is dilated cardiomyopathy (DCM), the leading global indication for heart transplantation. Our ...

Considering complexity in the genetic evaluation of dilated ...

Dilated cardiomyopathy (DCM) is a cardiovascular disease of genetic aetiology that causes substantial morbidity and mortality.

Genetic evaluation of cardiomyopathy: a clinical practice resource of ...

The primary cardiomyopathies covered in this document include hypertrophic cardiomyopathy (HCM), dilated cardiomyopathy (DCM), arrhythmogenic ...

Entry - #115200 - CARDIOMYOPATHY, DILATED, 1A; CMD1A - OMIM

Dilated cardiomyopathy (CMD) is characterized by cardiac dilatation and reduced systolic function. CMD is the most frequent form of cardiomyopathy and ...

Familial dilated cardiomyopathy - Genetics - MedlinePlus

Familial dilated cardiomyopathy is a genetic form of heart disease. It occurs when heart (cardiac) muscle becomes thin and weakened in at least one chamber of ...