Review article CRISPR/Cas9|based application for cancer therapy

CRISPR/Cas9 application in cancer therapy: a pioneering genome ...

During the last two decades, oncogenes, tumor suppressor genes, metabolism-related genes, and genes involved in resistance to chemo- and radiotherapy have been ...

Article "A Review on CRISPR/Cas9 as a Novel Technique for ...

One of the most recent and potentially effective technologies that has been used in last years for genetic modification and cancer therapy is Clustered ...

Therapeutic applications of CRISPR/Cas9 in breast cancer and ...

CRISPR/Cas9 and its associated catalytically inactivated dCas9 variants facilitate the knockout of overexpressed genes, correction of mutations in inactivated ...

CRISPR-Cas9, A Promising Therapeutic Tool for Cancer Therapy

It also plays a significant role in the development of complete genomic libraries for cancer patients. In this review, we have highlighted the involvement of ...

A review on genome editing by crispr-cas9 technique for cancer ...

Therefore, in the study we suggested the potential directions of the CRISPR-Cas9 system for future cancer therapy. ... Potential application for ...

(PDF) Application of CRISPR/Cas9 Technology in Cancer Treatment

CRISPR/Cas9 may treat gene-level tumors. CRISPR/Cas9-based personalized and targeted medicines may shape tumor treatment. This review examines ...

CRISPR-Cas9 for cancer therapy: Opportunities and challenges.

Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR)-Cas9-mediated genome editing technology has been extensively applied in various cell types ...

Optimization of CRISPR–Cas system for clinical cancer therapy

Altogether, the nonspecific RNase activity of Cas13 provides powerful tools for applications in nucleic acid detection, gene regulation, RNA ...

How CRISPR Is Changing Cancer Research and Treatment - NCI

CRISPR is a fairly new and highly precise gene editing tool that is changing cancer research and treatment. Researchers are using CRISPR to ...

Therapeutic potential of CRISPR/CAS9 genome modification in T ...

The production of CAR-T cells is one of the most critical applications of CRISPR-Cas9 technology in cancer immunotherapy. Abstract. Today, genome editing ...

Molecular and therapeutic effect of CRISPR in treating cancer

In most of the tumors this gene get mutated, CRISPR shows a promising results in CRISPR/Cas 9 induced double strand breaks in p53 gene tumor ...

Exploring the Advantages and Limitations of CRISPR-Cas in Breast ...

This is possibly due to the recent application of this gene editing system in cancer research. Despite the above, CRISPR-Cas9 constitutes a ...

CRISPR/Cas9 for cancer treatment: technology, clinical applications ...

CRISPR-Cas9 has shown great promise for cancer treatment in cancer immunotherapy, manipulation of cancer genome and epigenome and elimination or inactivation ...

Nanotechnology-based delivery of CRISPR/Cas9 for cancer treatment

Nanotechnology has greatly contributed to cancer drug delivery. Here, we present the action mechanisms of CRISPR/Cas9, its application in cancer therapy and ...

Genome editing: A perspective on the application of CRISPR/Cas9 ...

In addition, the review emphasizes on the potential application of this system in the treatment of different diseases, such as pulmonary, ...

Application of the CRISPR/Cas9 System to Drug Resistance in ...

The CRISPR/Cas9 system is poised to play an important role in preventing drug resistance in breast cancer therapy and will become an essential ...

CRISPR-Cas9 genome editing using targeted lipid nanoparticles for ...

Harnessing CRISPR-Cas9 technology for cancer therapeutics has been hampered by low editing efficiency in tumors and potential toxicity of ...

What is CRISPR-Cas9 and How is it Used in Cancer Research?

June concluded that editing of T cells using CRISPR-Cas9 technology was safe and feasible for cancer treatment. Further research will be ...

Advanced strategies for CRISPR/Cas9 delivery and applications in ...

The advent of CRISPR/Cas9 technology has transformed molecular biology and exhibits potential for gene modification and therapy in various cancer types.

CRISPR Clinical Trials: A 2024 Update - Innovative Genomics Institute

In late 2023, we saw the first-ever approval of CRISPR-based medicine: Casgevy, a cure for sickle cell disease (SCD) and transfusion-dependent beta thalassemia ...