Role of tumor–host interactions in interstitial diffusion of ...

Application of 3-D Microfluidic Models for Studying Mass Transport ...

Role of extracellular matrix assembly in interstitial transport in solid tumors. ... Role of tumor–host interactions in interstitial diffusion of.

Fluid mechanics in circulating tumour cells: Role in metastasis and ...

Because collagen I boosts mesenchymal motility, cancer cells could travel in the opposite direction of convective flow. The flow of interstitial fluid works in ...

Angiogenesis and Lymphangiogenesis in Tumors

Role of tumor-host interactions in interstitial diffusion of macromolecules: Cranial vs. subcutaneous tumors. Proc. Natl. Acad. Sci. 98: 4628. Abstract/FREE ...

Potential Role of FDG-PET Imaging in Understanding Tumor-Host ...

Thus, interstitialglucose concentrations at the tumor host interface ... tumor-host interaction. The models predict that in addition to increased ...

Reengineering the Physical Microenvironment of Tumors to Improve ...

vascular normalization), stress alleviation improves diffusion within the tumor interstitial space ... (2001) Role of tumor-host interactions in intersti- · tial ...

Towards extracellular matrix normalization for improved treatment of ...

Overall, the ECM re-organization, along with solid stress and high interstitial fluid pressure promote tumor progression and metastasis. Notably, the migration ...

The role of cancer-associated fibroblasts, solid stress and other ...

Interactions during which the tumor creates a microenvironment favourable for proliferation, for the recruitment of new blood vessels, and for ...

Role of extracellular matrix assembly in interstitial transport in solid ...

The extracellular matrix (ECM) may contribute to the drug resistance of a solid tumor by preventing the penetration of therapeutic agents. We measured ...

Defining the role of the tumor vasculature in antitumor immunity and ...

Cancer cells incite the formation of new blood and lymphatic vessels from preexisting vessels to cope with their high nutrient/oxygen demand and ...

Role of Extracellular Matrix in Development and Cancer Progression

On a microscopic level, the particular arrangement and orientation of ECM constituents form a tissue-specific microenvironment that plays a critical role in ...

Enhanced macromolecule diffusion deep in tumors after enzymatic ...

Little convective delivery occurs in solid tumors because of elevated interstitial fluid pressure as a consequence of vessel leakiness and the ...

Role of the tumor microenvironment in cancer hallmarks and ...

Interactions of TME stromal cells with cancer cells create a protective environment that promotes tumor growth in both cases (2,5). Tumor- ...

(PDF) Multiscale Measurements Distinguish Cellular and Interstitial ...

A critical step in the delivery of nanomedicines to tumour cells is transporting these particles through the extracellular matrix. Tumour-specific anticancer ...

effect of mechanical stress on tissue oxygenation, cancer cell ... - OUCI

... Role of tumor–host interactions in interstitial diffusion of macromolecules: cranial vs. subcutaneous tumors. Proc Natl Acad Sci USA 98:4628–4633 https ...

Role of Host Microenvironment in Angiogenesis and Microvascular ...

Collectively, host microenvironment is an important determinant of tumor gene expression and microvascular functions, and, thus, orthotopic breast tumor models ...

Diffusion and Convection in Collagen Gels - ResearchGate

As convection through tumor tissue is poor due to interstitial hypertension, diffusion becomes the major mode of species transport [15, 16]. Therefore, the ...

Tumor Host Interactions - University of Colorado School of Medicine

Understand interactions between tumor-intrinsic properties and immune recognition. Existing or treatment-driven tumor heterogeneity can facilitate immune ...

‪David Alan Berk‬ - ‪Google Acadèmic‬ - Google Scholar

Role of tumor–host interactions in interstitial diffusion of macromolecules: cranial vs. subcutaneous tumors. A Pluen, Y Boucher, S Ramanujan, TD McKee, T ...

Computational modelling suggests complex interactions between ...

The role of interstitial flow in tumour angiogenesis is not well understood. In principle, interstitial flow could affect angio- genesis in multiple ways ...

Tumor Cell-Organ Microenvironment Interactions in the ...

The pathogenesis of metastasis depends on multiple interactions of metastatic cells with favorable host homeostatic mechanisms. Interruption of one or more of ...