Single|cell multi|omics and lineage tracing to dissect cell fate ...

Application of New Lineage Tracing Techniques in Cardiovascular ...

With the advent of single-cell transcriptomics, a tremendous number of new cell types and subsets are recently discovered in different ...

Combined lineage tracing and scRNA-seq reveals unexpected first ...

TBX5 lineage tracing and high resolution single cell transcriptomics uncover the predominance of first heart field development during ...

Lineage tracing reveals fate bias and transcriptional memory in ...

We combined single-cell transcriptomics and lineage tracing to understand fate choice in human B cells. Using the antibody sequences of B ...

Using Single-Cell and Spatial Transcriptomes to Understand Stem ...

Embryonic development and stem cell differentiation provide a paradigm to understand the molecular regulation of coordinated cell fate determination and the ...

Exploring Cell Fate and Memory through Single-Cell Multi-Omic ...

Here, I talked about our recent work published in Cell titled "A mouse model with high clonal barcode diversity for joint lineage, ...

DNA Barcoding Technology for Lineage Recording and Tracing to ...

Haghverdi, L.; Ludwig, L.S. Single-Cell Multi-Omics and Lineage Tracing to Dissect Cell Fate Decision-Making. Stem Cell Rep. 2023, 18, 13–25. [Google ...

Mapping lineage-traced cells across time points with moslin - OUCI

Single-cell multi-omics and lineage tracing to dissect cell fate decision-making, Stem Cell Reports, № 18, с. 13 https://doi.org/10.1016/j.stemcr.2022.12 ...

Publications | Samantha Morris Lab

Multiomic single-cell lineage tracing to dissect fate-specific gene regulatory programs. ... single cells. ... Differentiation with Single-Cell Transcriptomics.

Clonal lineage tracing reveals mechanisms skewing CD8 + T cell ...

Using single-cell RNA and TCR sequencing, we traced the clonal expansion and differentiation of CD8+ T cells during chronic LCMV infection. We ...

Imaging cell lineage with a synthetic digital recording system - Science

... lineage from single cells: Genetic techniques for cell lineage tracking. ... Single-cell multi-omics and lineage tracing to dissect cell fate ...

Single-cell sequencing to multi-omics: technologies and applications

Lineage tracing can be deduced by the patterns of mutations shared between cells. The emergence of CRISPR/Cas9 technology facilitates the ...

Unravelling cellular relationships during development and ...

... lineage tracing (GESTALT) and single- cell ScarTrace (scScarTrace) unravelled the clonal origin of microglia and multipotent progenitor cells.

Beyond the Rainbow: A Review of Advanced Lineage Tracing ...

We will also discuss recent advances in computational biology, single-cell sequencing, and in situ-based lineage tracing methodologies.

Synergy of single-cell sequencing analyses and in vivo lineage ...

Here, we present our view on the utility of incorporating in vivo lineage-tracing approaches into single-cell sequencing omics studies. Single-cell ...

Cre-loxP-mediated genetic lineage tracing: Unraveling cell fate and ...

The Cre-loxP-mediated genetic lineage tracing system is essential for constructing the fate mapping of single-cell progeny or cell ...

Publications - Allen Discovery Center for Lineage Tracing

The field of single-cell RNA sequencing (scRNA-seq) has been paired with genomics, epigenomics, spatial omics, proteomics and imaging to achieve multimodal ...

Reconstructed Single-Cell Fate Trajectories Define Lineage ...

Hurley et al. show that a combination of single-cell transcriptomics, computational modeling, and DNA barcoding can map cell-fate trajectories,.

Using single-cell genomics to understand developmental processes ...

... and the future directions of cell lineage tracing and spatial gene expression analysis. Keywords cell fate; development; differentiation; single-cell RNA-seq;.

Dissecting Stem Cell Differentiation using Single Cell Expression ...

single cell transcriptomics is redefining lineages. ... lineages has also been observed by lineage tracing [51], so understanding how ... cell fate decisions ...

Current approaches to fate mapping and lineage tracing using ...

... fates of cells. Combined with powerful new advances in genomics and single-cell transcriptomics, the field of developmental biology is able ...