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Six years of mainstreaming germline genetic testing across cancer ...


Mainstream Germline Genetic Testing with Expanded Eligibility for ...

Conclusion Mainstream genetic testing of breast cancer patients facilitated by BCCs makes it feasible for a large health care system to expand ...

Mainstream Germline Genetic Testing with Expanded Eligibility for ...

Abstract Background This study evaluated a new mainstream genetic testing pathway for hereditary cancer, with expanded eligibility for early-stage breast ...

Germline genetic testing can benefit all cancer patients as a routine ...

Data from 250 pancreatic cancer patients from the landmark INTERCEPT study conducted at the Mayo Clinic found that nearly one in six patients ...

An Australian mainstream genetic testing program: Clinicians views ...

Germline genetic testing results can guide treatment decisions for oncology patients and are now offered to many cancer patients. Mainstream ...

Development of an Electronic Decision Aid Tool to Facilitate ...

The current literature underscores the importance of mainstream genetic testing in ovarian cancer patients, showcasing its positive impact on ...

Mainstreaming cancer genetics: A model integrating germline BRCA ...

Cancer specialists were comfortable with the model. Conclusions: The mainstreaming model proved effective, increasing uptake of genetic testing in eligible ...

Physician-ordered Genetic Testing for Cancer Patients

ABSTRACT: National guidelines recommend germline genetic testing for many cancer indications to inform treatment decisions for patients and ...

Population-based germline breast cancer gene association studies ...

Germline genetic testing, previously restricted to familial and young-onset breast cancer, is now offered increasingly broadly to patients with ...

A mainstreaming oncogenomics model: improving the identification ...

Genetic testing for colorectal cancer (CRC) targets deficient mismatch repair (dMMR) genes to identify Lynch syndrome (LS). In the CRC context, ...

Mainstreaming Cancer Genetics 2020 - Alberta Health Services

o Inclusions: Had Gyne-Oncology-ordered HBOC genetic testing within 1 year preceding Mainstreaming go-live (Feb 25, 2019) and went through ...

Uptake and acceptability of a mainstreaming model of hereditary ...

For example, models employing remote delivery of genetic counseling through telephone [6 ... germline cancer genetic test results. 10.1093/jnci/djy015. J Natl ...

Adherence to NCCN Genetic Testing Guidelines in Pancreatic ...

Sixty-six pts (44%) underwent GL testing: 42 (28%) at time of diagnosis with the remainder later in treatment. The rate of GL testing increased ...

Genetic Testing for Hereditary Cancer - UHCprovider.com

... (6-10% of testers over the study period). Women were less likely to ... all women with epithelial ovarian cancer should undergo germline genetic ...

Germline BRCA testing in pancreatic cancer: improving awareness ...

Experience in other familial cancers has shown that NGS is most likely to be cost effective if used for multigene panels rather than single-gene ...

The Feasibility of Implementing Mainstream Germline Genetic ...

Background: Non-genetic healthcare professionals can provide pre-test counseling and order germline genetic tests themselves, which is called mainstream ...

Mainstreaming cancer susceptibility gene testing — Knowledge Hub

Mainstreaming of constitutional (germline) testing has since been expanded to include patients with other cancer types, particularly those cancer types where ...

BGCS-BAGP-070920-final-v1.pdf

Mainstreamed genetic testing for women with ovarian cancer: First-year experience. J. Med. Genet.2019; 56, 195–198. Rust, K. et al. Routine germline BRCA1 ...

How and When to Consider Genetic Testing for Colon Cancer?

Over time, we have acquired more robust evidence and established guidelines on how to best manage patients with germline mutations in cancer sus- ceptibility ...

Cancer Genetics Risk Assessment and Counseling (PDQ®) - NCI

Cancer genetics risk assessment and genetic counseling includes family history, psychosocial assessments, and education on hereditary cancer ...

Implications of genetic testing and informed consent before and after ...

Core Tip: Mainstreaming has allowed for improved and readily available access to next generation sequencing testing in some regions of the world ...