Targeting the Molecular and Immunologic Features of ...

Small molecules as theranostic agents in cancer immunology

The various cell types and targets/signal pathways involved in cancer immunity supply prosperous potential targets of intervention for small-molecule-mediated ...

Molecular Oncology & Tumor Immunology | NYU Langone Health

applied approaches to cancer and immunity such as targeted tumor cell killing, tumor gene therapy, production of antitumor vaccines, and immunological and ...

Molecular Microbiology and Immunology Faculty : SLU

Research interests: Conventional dendritic cells (cDC) have crucial roles in priming effector T cells but cDC also have critical tolerogenic functions in the ...

KRASG12D-Mutated Metastatic Colorectal Cancer

KRASG12D-Mutated Metastatic Colorectal Cancer: Clinical, Molecular, Immunologic, and Prognostic Features of a New Emerging Targeted Alteration.

Targeting immunogenic cancer cell death by photodynamic therapy

The past decade has witnessed major breakthroughs in cancer immunotherapy. This development has been largely motivated by cancer cell evasion of immunological ...

Molecular Microbiology and Immunology | OHSU

Rodda delineated the diverse stromal populations that organize B cells functions in lymph nodes and defined the features ... targets for lung pathologies such as ...

Immunology & Cell Biology - Wiley Online Library

Immunology & Cell Biology (ICB) is the flagship journal of the ASI, publishing the latest research in immunology, cellular immunology, innate and adaptive ...

Finding Common Cause to Advance Immunotherapy Access with ...

Similarly, the TARGET program applies the core principles of teamwork and data sharing to early-phase cancer immunotherapy trials. It focuses on novel ...

Molecular targets in health and disease: focus on PI3-kinase

Presentation Research Lines Group Members Lab website Ana C. Carrera Group Leader Contact Research summary The focus of the team´s work...

Molecular Immunology Laboratory

To complement our genetic screens, we also perform high-throughput drug screens for agents that promote favourable states of T cell differentiation for anti- ...

Cancer Biology & Immunology Research Program

... functions of immune cells and immune tolerance. Featured Research. portrait of ... Targeting Pancreatic Cancer. A new study from Hollings researchers ...

Genetic dysregulation of immunologic and oncogenic signaling ...

Although surgery, radiation, and chemotherapy remain widely used forms of traditional cancer therapy, targeted and immune-based interventions ...

Research - Immunology - LUMC

Systemic counteraction of these hijacks often results in severe immune-related adverse events (irAEs). Molecular targeting approaches enable local ...

Immunology & Molecular Medicine

Using approaches from many disciplines and techniques as diverse as recombinant DNA, flow cytometry, physical chemistry, mouse transgenesis, and targeted ...

Immunology & Theranostics | City of Hope

This includes engineered radiolabeled antibodies for immunoPET imaging and radioimmunotherapy, in preclinical models as well as translation into pilot and phase ...

Cellular and molecular immunologic mechanisms in patients with ...

Mansouri, Y. ∙ Guttman-Yassky, E. Immune pathways in atopic dermatitis, and definition of biomarkers through broad and targeted therapeutics. J Clin Med. 2015 ...

Molecular Immunology Section | Frederick National Laboratory

A large portion of modern cancer research focuses on the ability of the immune system to destroy cancer cells using tumor-specific antibodies and ...

CTLA-4–mediated transendocytosis of costimulatory molecules ...

Although checkpoint blockade targeting cytotoxic T lymphocyte associated protein 4 (CTLA-4) and programed cell death 1 (PD-1) have changed ...

Molecular Components of the Immune System - Merck Manuals

Targeting of IL-3 receptor alpha chain with monoclonal antibodies or chimeric antigen receptor (CAR) T cells, which may be of benefit in patients with ...

Combinatorial Genetic, Stromal, and Immunologic Markers

Genetic analyses of pancreatic cancer revealed few currently actionable targets for therapeutic intervention (4–6). However, these analyses ...