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The protease SPRTN and SUMOylation coordinate DNA|protein ...


SUMO orchestrates multiple alternative DNA-protein crosslink repair ...

Vaz et al., SPRTN protease and SUMOylation coordinate DNA-protein crosslink repair to prevent genome instability. bioRxiv, 2020.2002 ...

A DNA-Dependent Protease Involved in DNA-Protein Crosslink Repair

Related articles (40). The protease SPRTN and SUMOylation coordinate DNA-protein crosslink repair to prevent genome instability. Ruggiano et ...

DNA-Protein Crosslink Proteolysis Repair. - Semantic Scholar

The protease SPRTN and SUMOylation coordinate DNA-protein crosslink repair to prevent genome instability · Biology, Medicine. Cell reports · 2021.

SUMO and the DNA damage response - Portland Press

... coordinated by ubiquitin and SUMO ... A.N.. , et al. (. 2021. ) The protease SPRTN and SUMOylation coordinate DNA-protein crosslink repair to prevent genome ...

SPRTN (SprT-like N-terminal domain)

The protease SPRTN and SUMOylation coordinate DNA-protein crosslink repair to prevent genome instability. 25. 35469923, 2022, Ubiquitin ...

‪Annamaria Ruggiano‬ - ‪Google Scholar‬

The protease SPRTN and SUMOylation coordinate DNA-protein crosslink repair to prevent genome instability. A Ruggiano, B Vaz, S Kilgas, M Popović, G Rodriguez ...

Full article: Multifaceted roles of SUMO in DNA metabolism

... protease specific for the ubiquitin-like Smt3 protein ... The protease SPRTN and SUMOylation coordinate DNA-protein crosslink repair to prevent genome instability ...

Quantitative Detection of DNA-Protein Crosslinks and Their Post ...

The protease SPRTN and SUMOylation coordinate DNA-protein crosslink repair to prevent genome instability. Cell Reports. 37 (10), 110080 ...

Enzymatic Processing of DNA–Protein Crosslinks - MDPI

The protease SPRTN and SUMOylation coordinate DNA-protein crosslink repair to prevent genome instability. Cell Rep. 2021, 37, 110080. [Google Scholar] ...

Mechanisms to Repair Stalled Topoisomerase II-DNA Covalent ...

(2020) SPRTN protease and SUMOylation coordinate DNA-protein crosslink repair to prevent genome instability. bioRxiv DOI: 10.1101/2020.02 ...

Ubiquitin signaling and the proteasome drive human DNA–protein ...

K. The protease SPRTN and SUMOylation coordinate DNA–protein crosslink repair to prevent genome instability . Cell Rep. 2021. ;. 37. : 110080.

Tyrosyl-DNA phosphodiesterase 1 (TDP1) and SPRTN protease ...

DNA–protein crosslinks (DPCs) are frequent and damaging DNA lesions that affect all DNA transactions, which in turn can lead to the ...

DNA–protein crosslink proteases in genome stability

Blue: SUMO/ubiquitin/proteasome binding. The catalytic residues in the protease domains are underlined. The sites of disease-associated mutations in SPRTN ( ...

Mechanism and function of DNA replication‐independent DNA ...

We show that the SUMO‐targeted ubiquitin ligase RNF4 defines a major pathway for ubiquitylation and proteasomal clearance of SUMOylated DPCs in the absence of ...

DNA protein crosslink proteolysis repair: From yeast to premature ...

SPRTN protease and SUMOylation coordinate DNA-protein crosslink repair to prevent genome instability · Biology, Medicine. bioRxiv · 2020.

SUMO in the regulation of DNA repair and transcription at nuclear ...

(2020) TEX264 coordinates p97- and SPRTN-mediated resolution of topoisomerase 1-DNA adducts. ... SUMO protease Ulp1. Mol Cell 51, 807–818 ...

SPRTN is a mammalian DNA-binding metalloprotease that resolves ...

The catalytic glutamic acid and zinc-coordinating histidines are indicated by bold text. (C) Yeast spot assay. Five-fold dilutions of wildtype, ...

Editorial: The repair of DNA-protein crosslinks. - Europe PMC

The protease SPRTN and SUMOylation coordinate DNA-protein crosslink repair to prevent genome instability. Ruggiano A, Vaz B, Kilgas S, Popović M, Rodriguez ...

Identifying ADP-Ribosylation as the Biochemical Signal that Marks ...

... SUMOylated to coordinate expression of DNA ... A ubiquitin switch controls autocatalytic inactivation of the DNA- protein crosslink repair protease SPRTN.

Quantification of Intracellular DNA–Protein Cross-Links with N7 ...

The Protease Sprtn and Sumoylation Coordinate DNA-Protein Crosslink Repair to Prevent Genome Instability. Cell Rep. 2021, 37, 110080 DOI ...