Allosteric regulation of Arf GTPases and their GEFs at the membrane ...

Autoactivation of small GTPases by the GEF–effector positive

: ARF GTPases and their GEFs and GAPs: concepts and ... Arno on model membranes in the presence of Arf effectors suggest control by.

The HUS box is required for allosteric regulation of the Sec7 Arf-GEF

The Golgi complex is the central membrane and protein-sort- ing station in eukaryotic cells. Activation of Arf (ADP-ribosyla- tion factor) GTPases is ...

Structural Insights into the Regulation Mechanism of Small GTPases ...

... membrane recruitment of Arf-family members with their activation by GEFs. ... membrane recruitment and allosteric activation of cytohesin family Arf GTPase ...

Sec7 regulatory domains scaffold autoinhibited and active ... - bioRxiv

... allosteric regulation of the Sec7 Arf-GEF. J ... Cherfils, Allosteric regulation of Arf GTPases and their GEFs at the membrane interface.

Arf GTPase activates the WAVE regulatory complex through a ...

Because Rac1 binding to the A site is sufficient to activate the WRC through an allosteric mechanism (46), the question remains: Does Arf1 ...

ARL3 activation requires the co-GEF BART and effector-mediated ...

(2016) Allosteric regulation of arf GTPases and their GEFs at the membrane interface. Small GTPases 7:283–296. https://doi.org/10.1080 ...

An ARF GTPase module promoting invasion and metastasis through ...

ARF GTPases function with GEFs and GAPs that control their nucleotide-association state (Fig. 1d). We observed an association of the GEF IQSEC1 ...

Structural basis for membrane recruitment and allosteric activation of ...

understood. Arf GTPases function in trafficking and cytoskeletal dynam- ... Donaldson JG, Jackson CL (2011) ARF family G proteins and their regulators: Roles in.

Arf GAPs as Regulators of the Actin Cytoskeleton—An Update - MDPI

... their relative activities to control machinery for cytoskeleton and membrane traffic. ... Ridley, A.J. Rho GTPases and actin dynamics in membrane ...

N-Terminal Hydrophobic Residues of the G-Protein ADP ...

Allosteric regulation of Arf GTPases and their GEFs at the membrane interface. Small GTPases 2016, 7 (4) , 283-296. https://doi.org/10.1080 ...

Taking a closer look at small GTPases at the membrane interface

... GTP. Activation of small GTPases by GDP/GTP exchange is tightly regulated by their guanine nucleotide exchange factors (GEFs). Outstanding questions in the ...

Search | VHL Regional Portal - BVS

12. Allosteric regulation of Arf GTPases and their GEFs at the membrane interface. Nawrotek, Agata; Zeghouf, Mahel; Cherfils, Jacqueline ...

The domain architecture of large guanine nucleotide exchange ...

A conserved scenario for the activation of Arf proteins by their GEFs? ... Chavrier P, Goud B: The role of ARF and Rab GTPases in membrane ...

Allosteric regulation of Arf GTPases and their GEFs at the membrane ...

Allosteric regulation of Arf GTPases and their GEFs at the membrane interface. scientific article published on 22 July 2016. Allosteric regulation of Arf ...

Arf GTPase Family - Addgene

... membrane, lipid droplets, the nucleus, and mitochondria. The activity of GTPases is regulated both upstream (by GEFs, guanine nucleotide exchange factors) ...

An evolutionary perspective on Arf family GTPases - HAL

... ARF GTPases and their GEFs and GAPs: concepts and challenges. ... membranes to regulate its activity. 23. More K, Klinger CM, Barlow ...

Structural elucidation of how ARF small GTPases induce membrane ...

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