Apoptosis in neurodegenerative disorders

6. Apoptosis in Neurodegenerative Disorders - J-Stage

Keywords: Parkinson's disease, neuronal death, apoptosis, Alzheimer's disease, Huntington's ... of apoptosis in various neurodegenerative disorders. Underthe.

The neuroprotective effects of targeting key factors of neuronal cell ...

Neurodegenerative diseases are mostly characterized by toxic protein aggregates with abnormal conformation within neurons or neuroglia, leading to memory, ...

Treating Neurodegenerative Conditions Through the Understanding ...

It is generally accepted that neuronal loss, in these diseases, occurs by the inappropriate activation of a cell-suicide process called apoptosis. Drugs that ...

Apoptosis in neurodegenerative disorders - OUCI

Widespread elimination of naturally occurring neuronal death in Bax-deficient mice. J. Neurosci. 18, 1428–1439 (1998).Direct evidence that the pro-apoptotic ...

Neuronal Life-and-Death Signaling, Apoptosis, and ...

Increasing evidence suggests that apoptotic biochemical cascades are involved in the dysfunction and death of neurons in neurodegenerative disorders.

Role of apoptosis in acute neurodegenerative disorders - IOS Press

Several recent studies suggest that a suicide-like phenomena similar to apoptosis or programmed cell death also contributes to the loss of neurons in stroke.

Apoptosis in Neurodegenerative Disease, Myocardial Infarction and ...

Over induce apoptosis is the cause of neurodegenerative disorder; Alzheimer's disease (AD) and perkinson's disease (PD) are the neurodegenerative disorder ...

Autophagy and Apoptosis Dysfunction in Neurodegenerative ... - DiVA

features of macroautophagy and apoptosis. Finally, their significance in the pathogenesis of neurodegenerative diseases as well as potential therapeutic ...

Apoptosis and its Role in Parkinson's Disease - Exon Publications

Apoptosis has been implicated as the main mechanism of neuronal death in Parkinson's disease. Apoptosis is mediated by a number of initiator and executioner ...

Apoptosis: A Key in Neurodegenerative Disorders - Ingenta Connect

Key Words: Neuronal apoptosis, apoptosis and neurodegeneration, mitochondrial apoptotic signaling, oxidative stress and apoptosis, apoptosis and ...

A neurodegenerative disease mutation that accelerates the ... - PNAS

This reduction in corpse number is not caused by reduced apoptosis, but instead by more rapid clearance of dying cells. Likewise, we found that macrophages ...

Autophagy and apoptosis dysfunction in neurodegenerative disorders

features of macroautophagy and apoptosis. Finally, their significance in the pathogenesis of neurodegenerative diseases as well as potential ...

ANALYSIS OF APOPTOSIS IN NEURODEGENERATIVE DISEASES ...

Faf1 is expressed during neurodevelopment and is involved in Apaf1-dependent caspase-3 activation in proneural cells.

Apoptosis in Neurodegenerative Diseases - OUCI

Anandatheerthavarada HK, Biswas G, Robin MA, Avadhani NG. Mitochondrial targeting and a novel transmembrane arrest of Alzheimer's amyloid precursor protein ...

Apoptotic mechanisms in Alzheimer neurofibrillary degeneration - JCI

Increasing evidence suggests that selective neuronal loss in neurodegenerative diseases involves activation of cysteine aspartyl proteases (caspases), which ...

Neuronal cell death in human neurodegenerative diseases and their ...

The absence of this precise control of cell number in tissues causes cancer (impaired apoptosis is a central step toward neoplasia). Pathologic stimuli can be ...

Neuronal apoptosis as a therapeutic target in neurodegenerative ...

Thus, although treatment of neurodegenerative disease by means of manipulating apoptosis is an area of much activity and holds promise for the future, clinical ...

What Is Neurodegenerative Disease? - CST BLOG: Lab Expectations

Acquiring Senescence/Cell Death: Mutations in proteins involved in the pathways of cell death including apoptosis, necroptosis, and autophagy are related to ...

Non-Coding RNAs and Neurodegenerative Diseases

Apoptosis can be known as a key factor in the pathogenesis of neurodegenerative disorders. In disease conditions, the rate of apoptosis expands and tissue ...

Planar cell polarity gene Fuz triggers apoptosis in ... - EMBO Press

Perturbation of various molecular and cellular processes is implicated in the pathology of polyQ diseases including the regulation of apoptosis and gene ...