Asthmatic and Normal Respiratory Epithelial Cells Respond ...

Barrier responses of human bronchial epithelial cells to grass pollen ...

The airway epithelium forms a physical, chemical and immunological barrier against inhaled environmental substances. In asthma, these barrier properties are ...

Bronchial epithelial cells produce IL-5 - UConn Health

and interleukin-6 and interleukin-8, in bronchial epithelial cells of patients with asthma, J. ... have normal antibody and cytotoxic T cell responses, Immunity 4 ...

Oxidative stress on airway epithelium permeability in asthma | JAA

In response to allergens, such as HDM and fungi, cell culture models of human bronchial epithelial cells show decreases in tight junction ...

Phenotypic Responses of Differentiated Asthmatic Human Airway ...

Human airway epithelial cells are the principal target of human rhinovirus (HRV), a common cold pathogen that triggers the majority of asthma exacerbations. The ...

Role of epithelial chemokines in the pathogenesis of airway ...

A disrupted immune response of airway epithelial cells induces the occurrence and development of complicated airway inflammation in asthma (4,5) ...

Bronchoconstriction: a potential missing link in airway remodelling

A growing body of literature indicates that airway epithelial cells cause pathophysiological processes when functionally altered by mechanical ...

Regulation of Immune Responses by Nonhematopoietic Cells in ...

In addition to their well-established roles in gas exchange and barrier function, lung epithelial cells express an armament of innate sensors ...

Airway epithelial cell response to RSV is mostly impaired in goblet ...

The type I interferon antiviral response of epithelial cells upon RSV infection is found to be reduced in asthma in most—but not all—studies.

Airway smooth muscle cells respond directly to inhaled ...

Together with the altered airway smooth muscle cells and myo-fibroblasts, reduced airway epithelial cell function and the lung infiltrated immune cells may keep ...

Research advances in airway remodeling in asthma: a narrative ...

Airway epithelial cells form the first physiological barrier of the respiratory tract against external environmental microbes, allergens, and ...

Asthma: Practice Essentials, Background, Anatomy

Antigen presentation by the dendritic cell with the lymphocyte and cytokine response leading to airway inflammation and asthma symptoms. ... asthma and normal ...

Airway epithelium–shifted mast cell infiltration regulates asthmatic ...

These results demonstrate that type 2 inflammation and indirect AHR in asthma are related to a shift in mast cell infiltration to the airway epithelium.

Airway epithelial response to RSV is impaired in multiciliated and ...

Goblet cells from asthma patients showed lower expression of genes involved in the interferon response. In multiciliated cells, an impairment of ...

Rhinovirus infection of airway epithelial cells uncovers the non ...

We hypothesized that airway epithelial cells could also mediate genetic susceptibility to asthma given they are the first line of defense against respiratory ...

Calcium Signaling in Airway Epithelial Cells - AHA Journals

Airway epithelial cells play an indispensable role in protecting the lung from inhaled pathogens and allergens by releasing an array of ...

Primary Small Airway Epithelial Cells; Asthma - PCS-301-011 | ATCC

Primary small airway epithelial cells are spindle-shaped that were isolated from the respiratory tract of a donor with asthma.

Differential bronchial epithelial response regulated by ΔNp63

In healthy bronchial tissue, ΔNp63-positive basal epithelial cells were covered with differentiated ΔNp63-negative cells but in the asthmatic airway, ΔNp63- ...

Rhinovirus-induced modulation of gene expression in bronchial ...

Genome-wide expression analysis of RV1A-infected primary bronchial epithelial cells from normal and asthmatic donors was performed to determine whether asthma ...

Asthmatic bronchial epithelial cells have a deficient innate immune ...

Virus infection induced late cell lysis in asthmatic cells but not in normal cells. Examination of the early cellular response to infection ...

Respiratory epithelial cell responses to SARS-CoV-2 in COVID-19

In the gas exchange portion of the lung, the alveolar type II epithelial cell is the main target cell type. Cell death and marked innate immune response during ...