- Diffusion maps for high|dimensional single|cell analysis of ...🔍
- Expression dynamics of repetitive DNA in early human embryonic ...🔍
- Understanding the Molecular Circuitry of Cell Lineage Specification ...🔍
- Single Cell Portal🔍
- Building and analyzing metacells in single|cell genomics data🔍
- High|throughput sequencing reveals hub genes for human early ...🔍
- Using Single|Cell and Spatial Transcriptomes to Understand Stem ...🔍
- The human embryo 🔍
Building a molecular reference map of the human embryo
Diffusion maps for high-dimensional single-cell analysis of ...
... developing mouse embryo, Guo etal. (2010) ... L. et al. . (. 2013. ). Single-cell RNA-Seq profiling of human preimplantation embryos and embryonic stem cells.
Expression dynamics of repetitive DNA in early human embryonic ...
Considering the fact that repeats constitute a large portion of our genome with reported links to human physiology and disease, a thorough ...
Understanding the Molecular Circuitry of Cell Lineage Specification ...
Knockdown of LSD1 results in differentiation of human embryonic stem cells derepressing several developmental genes [39]. ... developing mouse embryo [54,57].
... molecular profiling of tissues and organs. Here, we present an integrated ... human retina cell atlas (HRCA) of transcriptome and chromatin ...
Building and analyzing metacells in single-cell genomics data
Currently, millions of cells from complex biological tissues can be phenotypically profiled across multiple modalities. The scaling of ...
High-throughput sequencing reveals hub genes for human early ...
RNA-seq analysis was performed on normal and arrest embryos to study the changes of gene expression during early embryonic development. A total ...
Using Single-Cell and Spatial Transcriptomes to Understand Stem ...
Embryonic development and stem cell differentiation provide a paradigm to understand the molecular regulation of coordinated cell fate determination and the ...
The human embryo : novel perspectives in research and disease ...
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Researchers Create a Molecular Map of Every Cell in a Developing ...
Researchers from the University of Pennsylvania School of Arts and Sciences and the Perelman School of Medicine provide a molecular 'atlas' ...
Single-nucleus cross-tissue molecular reference maps to decipher ...
Here, we establish a framework for profiling multiple tissues across the human body at single-cell resolution using single nucleus RNA-Seq (snRNA-seq), and ...
Variability of Gene Expression Identifies Transcriptional Regulators ...
Using a published single cell RNA-seq data set of human embryos collected at four-cell, eight-cell, morula and blastocyst stages, we identified genes with the ...
Addressing the ethical issues raised by synthetic human entities with ...
The "14-day rule" for embryo research stipulates that experiments with intact human embryos must not allow them to develop beyond 14 days.
MGI-Mouse Gene Expression Database (GXD)
... map via Morpheus, a heat map visualization and analysis tool created at the ... Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)) ...
Human and mouse body maps · Functional genomics series · Single-cell ... Human reference epigenomes · Mouse reference epigenomes · Mouse development ...
Discrete domains of gene expression in germinal layers distinguish ...
... development and map the eventual location of folds or fissures. ... Patterns of mRNA expression for the indicated genes in the developing cerebral cortex of human ...
How to build a human - ProQuest
Gerrard et al. were then able to integrate this data into a sort of atlas that mapped the activity level of developmental genes across the embryo. This in turn ...
EMAGE mouse embryo spatial gene expression database
The process of mammalian development is highly complex, with an orchestra of interacting molecular networks, each coming into play during ...
An integrated atlas of human placental development delineates ...
The derivation of human trophoblast stem cells (hTSCs) (Okae et al., 2018) from both blastocyst and first trimester placental tissue has ...
Fate mapping is a method used in developmental biology to study the embryonic origin of various adult tissues and structures. The "fate" of each cell or ...
The Electron Microscopy Data Bank (EMDB) is a public repository for cryogenic-sample Electron Microscopy (cryoEM) volumes and representative tomograms.