Clinical Trials Using Dacarbazine

Phase 3 Study to Compare the Efficacy and Safety of Eribulin With ...

Phase 3 Study to Compare the Efficacy and Safety of Eribulin With Dacarbazine in Subjects With Soft Tissue Sarcoma ; Official Title. A Randomized, Open-label, ...

an open-label, randomised, non-inferiority trial - The Lancet

The role of bleomycin and dacarbazine in the ABVD regimen (ie, doxorubicin, bleomycin, vinblastine, and dacarbazine) has been questioned, ...

Dacarbazine: MedlinePlus Drug Information

Dacarbazine injection must be given in a hospital or medical facility under the supervision of a doctor who is experienced in giving chemotherapy medications ...

Dacarbazine - Wikipedia

Dacarbazine, also known as imidazole carboxamide and sold under the brand name DTIC-Dome, is a chemotherapy medication used in the treatment of melanoma and ...

Nivolumab improved survival vs dacarbazine in patients with ...

This phase 3 study compared nivolumab vs dacarbazine in treatment-naïve patients with BRAF wild-type metastatic melanoma.

Dacarbazine-Loaded Targeted Polymeric Nanoparticles for ...

However, the hydrophobicity, photosensitivity, instability, and toxicity to normal cells of DTIC limit its efficacy in treating MM. In the ...

Phase II Clinical Trial of Camrelizumab Combined with AVD ...

Phase II Clinical Trial of Camrelizumab Combined with AVD (Epirubicin, Vincristine and Dacarbazine) in the First-Line Treatment for Patients ...

Dacarbazine - Leiomyosarcoma.info

Dacarbazine is an approved drug for use with soft tissue sarcomas. ... NOW you can save this search to a folder on your hard drive as "Dacarbazine Clinical Trials ...

Beneficial Use of the Combination of Gemcitabine and Dacarbazine ...

Gemcitabine and dacarbazine treatment administration dosage was based on the comparative phase II clinical trial carried out by X. García-Del-Muro et al. [22].

337-Melanoma metastatic dacarbazine SUPERSEDED - eviQ

No drug-related deaths or gastrointestinal perforations occurred in the ipilimumab-dacarbazine group. CONCLUSIONS: Ipilimumab (at a dose of 10 mg per kilogram) ...

Phase 3 Study to Compare the Efficacy and Safety of Eribulin With ...

Phase 3 Study to Compare the Efficacy and Safety of Eribulin With Dacarbazine in Subjects With Soft Tissue Sarcoma · Purpose · Official Title · Stanford ...

Phase II study of dacarbazine given with modern prophylactic anti ...

In this single-arm, phase II study, dacarbazine 850 mg/m 2 was given on day 1 of each 3-week cycle until disease progression or intolerance.

Melanoma | Study 11538 | Bayer - Clinical Trials Explorer

- Subjects with advanced, metastatic, histologically confirmed melanoma, for whom treatment with dacarbazine is considered medically acceptab... More. Exclusion ...

Dacarbazine (DTIC, DTIC-Dome®) | OncoLink

There is a very low risk of developing another type of cancer, including fibrosarcoma, sarcoma, or angiosarcoma due to treatment with this ...

Brentuximab-5019 | Clinical Trial Summary

During the study, pediatric participants with HL will take Brentuximab Vedotin injection and AVD treatment (doxorubicin hydrochloride, vinblastine sulfate, and ...

A Phase I/II Study of Dasatinib and Dacarbazine - ClinicalTrials.Veeva

Dasatinib and Dacarbazine (DTIC). The first cohort was a dasatinib dose of 50 mg by mouth (PO) twice a day (BID) given days 2-19 with DTIC given ...

EU Clinical Trials Register

A Phase 3, Randomized, Double-Blind Study of BMS-936558 vs Dacarbazine in Subjects with Previously Untreated Unresectable or Metastatic ...

New Drugs Stir Debate on Rules of Clinical Trials

Only months before, a new drug had shown that it could safely slow the cancer's progress in certain patients. Both cousins had the type of tumor ...

ARRY-142886) (Hyd-Sulfate) in Metastatic Uveal Melanoma (SUMIT)

Any prior investigational therapy comprising inhibitors of RAS, RAF or MEK at any time,; Previous treatment with dacarbazine. ... -Clinical judgement by the ...

DTIC Dome (dacarbazine) dosing, indications, interactions, adverse ...

USES: Dacarbazine is used to treat certain types of cancer, such as skin cancer and Hodgkin's disease. It is a cancer chemotherapy drug that is used to slow or ...