Coagulome and the tumor microenvironment

Molecular Landscape of the Coagulome of Oral Squamous Cell ...

... coagulation and fibrinolysis. We aimed to study the coagulome of Oral Squamous Cell Carcinoma (OSCC) and examine its link to the tumor microenvironment (TME).

Tissue factor as a new target for tumor therapy—killing two birds with ...

... tumor microenvironment (2-7). In addition to the coagulation process, increased TF expression has been observed more often in malignant ...

Molecular Landscape of the Coagulome of Oral Squamous Cell ...

We aimed to study the coagulome of Oral Squamous Cell Carcinoma (OSCC) and examine its link to the tumor microenvironment (TME). Methods: We used data from bulk ...

Local blood coagulation drives cancer cell arrest and brain ...

Clot formation in brain microvessels occurred frequently (>95%) and specifically at intravascularly arrested cancer cells, allowing their long- ...

The Tumor Coagulome as a Transcriptional Target and a Potential ...

Keywords: glucocorticoids; tumor coagulome; tumor microenvironment. Cancers 2023, 15, 1531. https://doi.org/10.3390/cancers15051531 · https ...

Exploring the crosstalk between endothelial cells, immune ... - Nature

... coagulation, and promoting angiogenesis [7]. Moreover, ECs play ... Targeting tumor microenvironment for cancer therapy. Int J Mol Sci ...

Tissue Factor and PAR2 Signaling in the Tumor Microenvironment

Metastatic tumor cells use additional signaling networks of the coagulation cascade by activating PAR1 through thrombin or the ternary TF-VIIa- ...

The Coagulome and the TME - LinkedIn

There are many different relationships between cancer cells, the tumor microenvironment, and the coagulome that have been reported in recent ...

The coagulome of oral squamous cell carcinoma: examining...

It also brought to light the intimate and reciprocal regulation between coagulation/fibrinolysis and the tumor microenvironment (TME). Summary. OSCC have a ...

Targeting coagulation to unlock antitumor immunity?

We recently applied systems biology and genomics to explore the regulation of the tumor immune microenvironment by coagulation.

OUH - Publications - OUS-research

The breast cancer coagulome in the tumor microenvironment and its role in prognosis and treatment response to chemotherapy ... Coagulation factor V is a marker of ...

A pan-cancer analysis of the human tumor coagulome and its link to ...

Document Type: Article ; Subject Terms: *TUMOR microenvironment *GENES *THROMBOEMBOLISM *TUMORS *GENE clusters ; Keywords: Cancer-associated thrombosis. Coagulome

Myeloid cell–synthesized coagulation factor X dampens antitumor ...

Immune evasion in the tumor microenvironment (TME) is a crucial barrier for effective cancer therapy, and plasticity of innate immune cells ...

Mari Tinholt on LinkedIn: The breast cancer coagulome in the tumor ...

This is only a scratch on the surface on understanding the intricate ways of the tumour microenvironment in breast cancer and I am excited to ...

Inhibition of tissue factor signaling suppresses tumor growth | Blood

Coagulation activation by tissue factor (TF) is implicated in cancer progression, cancer-associated thrombosis and metastasis. The role of direct TF signal.

What is the tumor microenvironment? | MD Anderson Cancer Center

The tumor microenvironment is the ecosystem that surrounds a tumor inside the body. It includes immune cells, the extracellular matrix, blood vessels and other ...

Department of Cancer Biology - Tumor Microenvironment

Tumor Microenvironment. Tumors require complex interactions with surrounding blood vessels, immune cells, supportive tissue structures and cell types that ...

Tumor Microenvironment - Memorial Sloan Kettering Cancer Center

Tumor Microenvironment. Share. tumor in microenvironment. Cancer cells do not act alone. They enlist the body's normal cells, molecules, and blood vessels ...

Tumor Microenvironment Working Group (TME) | AACR Scientific ...

The mission of the Tumor Microenvironment Working Group (TME) is to provide an opportunity for a diverse group of scientists with a common interest in the ...