Comprehensive analysis of chromothripsis in 2

Insight into the Molecular Basis Underlying Chromothripsis - MDPI

In case 1 and case 2, six broken chromosomes were involved in a complex ... Comprehensive analysis of chromothripsis in 2,658 human cancers using whole-genome ...

AML with complex karyotype: extreme genomic complexity revealed ...

... 2). In summary, our filtering strategy yielded a high ... Comprehensive analysis of chromothripsis in 2,658 human cancers using whole-genome sequencing.

Constitutional Chromothripsis on Chromosome 2: A Rare Case with ...

A summary of the clinical presentation among patients with 2q37 syndrome (OMIM # 600430), and case reports on complex 2p25 duplication and 2q37 ...

Chromothripsis is correlated with reduced cytotoxic immune ...

The TMB was modest and significantly higher in tumors with chromothripsis (median -8.62 × 10−2 ... Comprehensive analysis of chromothripsis in ...

Research progress on chromothripsis and tumorigenesis

Chromothripsis is a complex genomic rearrangement event ... Comprehensive analysis of chromothripsis in 2 658 human cancers using whole-genome sequencing[J].

Copy number signatures predict chromothripsis and clinical ...

Comprehensive analysis of chromothripsis in 2,658 human cancers using whole-genome sequencing. Nat. Genet. 52, 331–341. (2020). 2. Korbel, J. O. & Campbell ...

The Fanconi anemia pathway induces chromothripsis and ecDNA ...

2. Cortés-Ciriano, I. ∙ Lee, J.J.K. ∙ Xi, R. ... Comprehensive analysis of chromothripsis in 2,658 human cancers using whole-genome sequencing. Nat. Genet ...

[PDF] Chromothripsis and DNA Repair Disorders | Semantic Scholar

... chromothRIpsis. Expand. 46 Citations. Add to Library. Alert. 2 Excerpts. Comprehensive analysis of chromothripsis in 2,658 human cancers using whole-genome ...

parklab/ShatterSeek - GitHub

2 years ago. documentation.pdf · documentation.pdf · tutorial ... Comprehensive analysis of chromothripsis in 2,658 human cancers using whole-genome sequencing.

Chromothripsis Rearrangements Are Informed by 3D-Genome ...

Comprehensive analysis of chromothripsis in 2, 658 human cancers using whole-genome sequencing Nat. Genet. 2020 52 3 331-341. Crossref · Google ...

On the Complexity of Mechanisms and Consequences of ... - Frontiers

In the present review, we focus on the phenomenon of chromothripsis, a new type of complex chromosomal rearrangements ... Chromothripsis is typical for 2 ...

Full article: Understanding the molecular mechanisms underlying ...

performed a comprehensive analysis ... There is evidence for each model, including sequencing of several hundred chromothripsis breakpoints in cancer genomes and ...

Chromothripsis in acute myeloid leukemia: biological features and ...

A study on. 22,000 cases of primary tumors highlighted an overall incidence of chromothripsis between 2 and 3% [21]. During mitosis ...

Chromothripsis | Encyclopedia MDPI

Figure 2. Scheme of multiple complex chromosomal rearrangements in chromoplexy. Chromoplexy involves linked translocations of multiple chromosomes. As a result ...

Chromothripsis is linked to TP53 alteration, cell cycle impairment ...

The 2-year estimated survival rates for chromothripsis-positive versus chromothripsis ... analysis,5 chromothripsis provides additional ...

Chromothripsis-like chromosomal rearrangements induced by ...

Furthermore, whole genome sequencing analysis revealed multiple de novo complex chromosomal rearrangements localized in chromosomes 2, 5, 7, and ...

Copy number variations and constitutional chromothripsis (Review)

Introduction. Following the complete sequencing and analysis of the human genome, Snijders et al (1) assembled microarrays for genome-wide ...

Chromothripsis—Explosion in Genetic Science - MDPI

Comprehensive analysis of chromothripsis in 2,658 human cancers using whole-genome sequencing. ... DNA copy number analysis of Grade II-III and Grade IV ...

p624: chromothripsis in patients with cll and complex karyotype

To analyze the genome complexity associated with chromothripsis and the patterns of rearrangements detected by OGM; 2. To determine the prognostic impact of ...

Pan-cancer analysis of chromothripsis-related gene expression ...

Cortes-Ciriano, Comprehensive analysis of chromothripsis in 2,658 human ... 2 https://doi.org/10.18632/oncoscience.178; Nazaryan-Petersen ...