Comprehensive analysis of chromothripsis in 2

Comprehensive analysis of chromothripsis in 2,658 human cancers ...

Applying this criterion to CN profiles inferred from SNP arrays, chromothripsis was initially estimated to occur in at least 2–3% of human ...

Comprehensive analysis of chromothripsis in 2658 human cancers ...

doi: 10.1038/s41588-019-0576-7. Epub 2020 Feb 5. Authors. Isidro Cortés-Ciriano 1 2 ...

Comprehensive analysis of chromothripsis in 2,658 human cancers ...

About half of the chromothripsis events co-localize with other genomic alterations (Fig. 1 and Supplementary Figs. 1, 2). There is evidence across multiple ...

Comprehensive analysis of chromothripsis in 2,658 human ... - bioRxiv

Chromothripsis affects only a single chromosome in 40.2% of the tumors with chromothripsis (Fig. 2a-c and. Supplementary Figs. 1-2). A large ...

Comprehensive analysis of chromothripsis in 2,658 human cancers ...

Although chromosome shattering and reassembly has been experimentally demonstrated to generate chromothripsis2, template-switching DNA- ...

Abstract LB-378: Comprehensive analysis of chromothripsis in 2658 ...

Abstract LB-378: Comprehensive analysis of chromothripsis in 2,658 human cancers using whole-genome sequencing ... CrossRef (2). Email alerts.

Comprehensive analysis of chromothripsis in 2,658 human cancers ...

Although chromosome shattering and reassembly has been experimentally demonstrated to generate chromothripsis, template-switching DNA-replication errors can ...

Comprehensive analysis of chromothripsis in 2658 human cancers ...

Here, as part of the Pan-Cancer Analysis of Whole Genomes (PCAWG) Consortium of the International Cancer Genome Consortium (ICGC) and The Cancer Genome Atlas ( ...

Supplementary Note Comprehensive analysis of chromothripsis in ...

For instance, if the chromothripsis regions in chromosome 1 and 2 are linked, and those detected in chromosome 2 are also linked to a chromothripsis region in ...

Comprehensive analysis of chromothripsis in 2,658 human cancers ...

(d) Scaled Circos plot representing the chromothripsis event in patient DO13971 (TCGA-06-0221; CNS-GBM) involving chromosomes 2 and 12, leading to the ...

Comprehensive analysis of chromothripsis in 2658 human cancers ...

Here, we analyze the patterns of chromothripsis across 2,658 tumors spanning 39 cancer types using whole-genome sequencing data. We find that chromothripsis ...

Comprehensive analysis of chromothripsis in 2,658 human cancers ...

Chromothripsis is a mutational phenomenon characterized by massive, clustered genomic rearrangements that occurs in cancer and other diseases.

(PDF) Comprehensive analysis of chromothripsis in 2,658 human ...

Analysis of whole-genome sequencing data across 2,658 tumors spanning 38 cancer types shows that chromothripsis is pervasive, with a frequency ...

Pan-cancer analysis of chromothripsis-related gene expression ...

Homologous recombination deficiency (HRD) is broadly defined in clinic, ranging from deleterious mutations in single HRR genes (i.e. BRCA1/2) to complex genomic ...

Comprehensive analysis of chromothripsis in 2,658 human cancers ...

Comprehensive analysis of chromothripsis in 2,658 human cancers using whole-genome sequencing. Check holdings Joint Library Facility (Use the Get a Scan ...

Chromothripsis, DNA repair and checkpoints defects - ScienceDirect

2. Chromothripsis and related complex chromosomal rearrangements. Chromothripsis is one of three forms of complex chromosomal rearrangements, classified ...

Comprehensive analysis of chromothripsis in 2,658 human cancers ...

Bioscience, Natural Resources & Public Health Library · 1 (Apr-Aug 1992). Item in place (0 requests). Loanable. v. · 2 (Sept-Dec 1992). Item in place (0 requests).

Chromothripsis is rare in IDH-mutant gliomas compared to IDH-wild ...

... analysis (OS not reached in grade 2 tumors). ... Comprehensive analysis of chromothripsis in 2,658 human cancers using whole-genome sequencing .

Comprehensive analysis of chromothripsis in 2,658 human cancers ...

Comprehensive analysis of chromothripsis in 2,658 human cancers using whole-genome sequencing. Isidro Cortés-Ciriano. ,. Jake June-Koo Lee. ,. Ruibin Xi. et ...

Comprehensive analysis of chromothripsis in 2,658 human cancers ...

Abstract. Chromothripsis is a mutational phenomenon characterized by massive, clustered genomic rearrangements that occurs in cancer and other ...