- Knockdown of GnT|Va expression inhibits ligand|induced ...🔍
- Structure and dynamics of the EGFR/HER2 heterodimer🔍
- The Role of BCA2 in the Endocytic Trafficking of EGFR and ...🔍
- Endocytic Adaptor Protein HIP1R Controls Intracellular Trafficking of ...🔍
- Regulation of epidermal growth factor receptor signalling by ...🔍
- Measurement of Epidermal Growth Factor Receptor|Derived Signals ...🔍
- Mutual Regulation of Receptor|Mediated Cell Signalling and ...🔍
- Epidermal Growth Factor Receptor Cell Proliferation Signaling ...🔍
Control of epidermal growth factor receptor endocytosis by receptor ...
Knockdown of GnT-Va expression inhibits ligand-induced ...
To study in detail the regulation of signaling of the EGF receptor (EGFR) by GlcNAcβ(1,6)Man branching, we utilized specific siRNA to selectively knockdown GnT- ...
Structure and dynamics of the EGFR/HER2 heterodimer - Nature
Unlike EGFR, HER2 does not change its membrane dynamics or undergo endocytosis upon EGF activation; moreover, it helps to retain EGFR on the ...
The Role of BCA2 in the Endocytic Trafficking of EGFR and ...
BCA2 over-expressing cells stimulated with EGF exhibited reduced lysosomal degradation of both this ligand and its receptor. Signalling downstream of EGFR in ...
Endocytic Adaptor Protein HIP1R Controls Intracellular Trafficking of ...
In HEK293T cells, overexpression of HIP1 or HIP1R stabilizes the pools of growth factor receptors, such as EGFR and platelet-derived growth factor-β receptor ( ...
Regulation of epidermal growth factor receptor signalling by ...
The epidermal growth factor receptor (EGFR) is the founding member of the ErbB receptor tyrosine kinase (RTK) family. EGFR signalling controls key cellular ...
Measurement of Epidermal Growth Factor Receptor-Derived Signals ...
Upon EGF binding at the plasma membrane, EGFR is internalized by clathrin-mediated endocytosis following recruitment to clathrin-coated pits (CCPs). Further, ...
Mutual Regulation of Receptor-Mediated Cell Signalling and ...
EGFR is overexpressed or hyper activated in many epithelial tumors and plays important roles in cancer development and progression [12]. The activated receptors ...
Epidermal Growth Factor Receptor Cell Proliferation Signaling ...
Following endocytosis, endocytic sorting generally targets receptors bound with EGF for lysosomal degradation or recycling, with HB-EGF and BTC for lysosomal ...
Regulation of signal transduction by endocytosis Brian P Ceresa ...
Abbreviations. β2AR β2 adrenergic receptor. EBP50. ERM-binding phosphoprotein-50. EGF epidermal growth factor. EGFR epidermal growth factor receptor.
Gαs protein binds ubiquitin to regulate epidermal growth factor ...
Mutation of the UIM in Gαs confirmed the importance of ubiquitin interaction for the sorting of epidermal growth factor receptor (EGFR) into ILVs for lysosomal ...
Proteomic Analysis of the Epidermal Growth Factor Receptor (EGFR ...
Activated EGFR is internalized by endocytosis and then either recycled back to the cell surface or degraded in the lysosome. EGFR internalization and recycling ...
Molecular Mechanisms that Regulate Epidermal Growth Factor ...
The Epidermal Growth Factor Receptor (EGFR) is the prototypical receptor tyrosine kinase (RTK). These cell surface receptors are integral membrane proteins ...
Increased Expression of Epidermal Growth Factor Receptor Induces ...
The epidermal growth factor receptor (EGFR) is a transmembrane receptor tyrosine kinase that is involved in the regulation of the proliferation, motility, and ...
EPS15 - Epidermal growth factor receptor substrate 15 - UniProt
... regulation of mitogenic signals and control of cell proliferation ... Involved in endocytosis of integrin beta-1 (ITGB1) and transferrin receptor ...
Regulation of the EGF Transcriptional Response by Endocytic Sorting
Ligand binding to the epidermal growth factor receptor (EGFR) triggers the endocytosis (internalization) of the receptor, which can be degraded or recycled back ...
P130Cas Attenuates Epidermal Growth Factor (EGF) Receptor ...
Endocytosis controls localization-specific signal transduction via epidermal growth factor receptor (EGFR), as well as downregulation of that receptor.
Epidermal growth factor receptor downregulation by small ...
Selected orientations of non-competitive heterodimers decrease EGFR levels by up to 80% in multiple cell types, without activating receptor signaling.
The EGF receptor tyrosine protein kinases - YouTube
The most important family of receptor tyrosine kinases is the family of the receptors for EGF (Epidermal Growth Factor).
Fruit Fly Studies Illuminate Congenital Defects - Mirage News
"This increased our interest in the epidermal growth factor receptor (EGFR) pathway because previous work indicated that it may be regulated by ...
EGFR Endocytosis: More Than Meets the Eye | Oncotarget - YouTube
Oncotarget published this trending editorial perspective on April 10, 2023 in Volume 14, entitled, “EGFR endocytosis: more than meets the ...