Controlling NK Cell Responses

Coordinated Viral Control by Cytotoxic Lymphocytes Ensures ...

Natural killer (NK) cells play a critical role in controlling viral infections, coordinating the response of innate and adaptive immune ...

Actin retrograde flow controls natural killer cell response by ...

Actin retrograde flow regulates SHP‐1 conformation and enzymatic activity upon inhibitory receptor engagement, thereby controlling NK cell mediated ...

Control of NK cell tolerance in MHC class I-deficiency by regulated ...

NK cell activation is tightly controlled by germline-encoded activating and inhibitory receptors. Activating receptors (AR) recognize microbial ...

Innate receptors modulating adaptive T cell responses: KIR-HLA ...

Although perforin+ NK cells do not reside in secondary lymphoid organs (Dogra et al. 2020), upon activation during viral infections, type I ...

Monocytes control natural killer cell differentiation to effector ...

Natural killer (NK) cells are innate lymphocytes that participate in the regulation of immune responses and in immunologic surveillance of ...

Study reveals how to activate natural killer cells to protect against ...

Interactions between NK cells and ECM proteins lead to an immediate switch in NK cell function from killer cells to helper cells when they exit ...

Natural killer cells as a therapeutic tool for infectious diseases

Natural Killer (NK) cells are involved in the host immune response against infections due to viral, bacterial and fungal pathogens, all of which ...

Genetically coupled receptor–ligand pair NKp80-AICL enables ...

Previous studies showed that NKp80 augments NK cell responses toward malignant and nonmalignant myeloid cells. Here, we report that resting human NK cells not ...

Cytokine-induced memory-like natural killer cells - PNAS

Here, we have discovered another layer of complexity to the innate immune response with the finding that NK cells can develop memory-like ...

Immunometabolism of T cells and NK cells: metabolic control of ...

Generally, Th17 effector cells promote autoimmunity while regulatory T (Treg) cells suppress these responses [8,9,10,11,12,13]. Similarly, NK ...

NK Cells Control Tumor-Promoting Function of Neutrophils in Mice

NK cells control the tumor-promoting function of neutrophils via an IFNγ-mediated mechanism. Therefore, tumor progression in an NK cell–depleted host is ...

Human natural killer cells: Form, function, and development

Human natural killer (NK) cells are innate lymphoid cells that mediate important effector functions in the control of viral infection and malignancy.

"Epigenetic drug screen of natural killer cells identified compounds ...

... NK cell function or provide novel therapies for tolerizing or priming innate immune responses ... natural killer cells identified compounds controlling ...

Natural Killer Cells Promote Early CD8 T Cell Responses ... - PLOS

Conversely, exogenous IFN-α administration in resistant animals ablates cDCs and delays CD8 T cell activation in the face of NK cell control of viral ...

Evaluating expression patterns of multiple inhibitory and stimulatory ...

Natural killer (NK) cells are an important component of the innate immune system and constitute a frontline defense in the killing of ...

How do natural killer cells target cancer? - YouTube

This animation demonstrates INmune Bio's research which focuses on the signals needed to transition NK cells from rest to lytic function, ...

HIV-1 Elite Controllers Are Characterized by Elevated...

NK cells are innate immune cells that secrete cytotoxic proteins to control viral infection and tumor growth. ... NK cells are phenotypically identified by the ...

Spatial colocalization and combined survival benefit of natural killer ...

NK cells kill MHC-I-deficient tumor cells, and although previous work indicated their presence at NSCLC margins, they were functionally impaired. Within, we ...

Immune system explained - Better Health Channel

deal with cell products that otherwise would result in disease or disorders ... Immunisation works by copying the body's natural immune response. A vaccine ...

Immune function of NK cells - YouTube

This video talks about Natural Killer cells and the functions of Natural killer cells. # Immune function of NK cells.