- Insights into Protein–DNA Interactions through Structure Network ...🔍
- Physicochemical models of protein–DNA binding with ...🔍
- Transient DNA binding to gapped DNA substrates links ...🔍
- DNA|binding domain🔍
- Specificity🔍
- Studying protein|DNA interactions with mass photometry🔍
- DNA|Protein interactions🔍
- A Case Study with Mycobacterium DNA Binding Protein🔍
DNA–DNA interactions
Insights into Protein–DNA Interactions through Structure Network ...
The present graph-based method provides a deeper insight into the analysis of the protein–DNA recognition mechanisms by throwing more light on the nature and ...
Physicochemical models of protein–DNA binding with ... - PNAS
We introduce models that directly and precisely represent physicochemical readout, which is, importantly, not restricted to standard Watson–Crick base pairs.
Transient DNA binding to gapped DNA substrates links ... - bioRxiv
Here we provide the missing link by introducing a single-molecule imaging method (Gap-Seq) that interrogates DNA sequences via transient binding ...
DNA-binding domain - Wikipedia
DNA-binding domain ... A DNA-binding domain (DBD) is an independently folded protein domain that contains at least one structural motif that recognizes double- or ...
Specificity, free energy and information content in protein–DNA ...
Experimental approaches typically analyze a protein–DNA interaction by measuring the free energy of binding under a variety of conditions.
Studying protein-DNA interactions with mass photometry - Refeyn
Mass photometry enables the accurate mass measurement of different biomolecules in solution, using light. Ananya and her colleagues study DNA ...
DNA-Protein interactions - YouTube
Subject: Biophysics Paper: Biomolecules and their interactions.
A Case Study with Mycobacterium DNA Binding Protein
We have shown that, when a kinetic bottleneck is applied, the binding mechanism showed cooperative binding (n = 2.72) at lower temperatures.
Repulsive DNA-DNA Interactions Accelerate Viral DNA Packaging ...
Abstract. We use optical tweezers to study the effect of attractive versus repulsive DNA-DNA interactions on motor-driven viral packaging.
Artificial Intelligence Reveals Protein-DNA Interactions - SynBioBeta
The feedback between experiments and AI means that the field is moving from identifying all DNA-binding sites on a protein or all proteins that ...
Genome-Wide Analysis of Protein-DNA Interactions | Annual Reviews
Abstract The human genome is predominantly composed of nonprotein-coding sequences whose function remains largely undefined.
Dam it's good! DamID profiling of protein‐DNA interactions - Aughey
DamID has emerged as one of the most comprehensive and versatile methods available for profiling protein–DNA interactions on a genomic scale.
Interpretable Protein-DNA Interactions Captured by Structure-based ...
We present IDEA, an interpretable residue-level biophysical model capable of predicting binding sites and strengths of DNA-binding proteins across the genome.
Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).
Analysis of DNA interactions and GC content with energy ...
GC content is a contributing factor to the stability of nucleic acids due to hydrogen bonding. More hydrogen bonding generally results in greater stability.
Purification or Removal of DNA-Binding Proteins - Sigma-Aldrich
Remove ionically bound proteins by washing with 0.5 CV of 2 M NaCl for 10 to 15 min. Remove precipitated or denatured proteins by washing with 4 CV of 100 mM ...
Additive Modulation of DNA-DNA Interactions by Interstitial Ions
The key finding of this study is that DNA-DNA forces are observed to linearly depend on the partition of interstitial ions, suggesting the dominant role of ion ...
DNA-DNA interactions in tight supercoils are described by a small ...
We have examined the interactions between DNA helices in plectonemic supercoils using magnetic tweezers, coarse-grained Monte Carlo and atomistic molecular ...
DNA Protein Interactions Basic Concept - YouTube
This video gives an overview of the different structural aspects of DNA - protein interactions. If you liked the video please hit the like ...
Using C-Trap® to unravel different binding modes of ... - LUMICKS
The researchers employed the C-Trap ® , a dynamic single-molecule method, to visualize in real-time the diffusion and binding of HU molecules along the DNA.