- Tracking the embryonic stem cell transition from ground state ...🔍
- Chromatin and Epigenetic Rearrangements in Embryonic Stem Cell ...🔍
- Wandering along the epigenetic timeline🔍
- Catenin and Activating TCFs Reconstitutes Ground State ...🔍
- Stem Cell Epigenetics🔍
- Otx2 and Oct4 drive early enhancer activation during embryonic ...🔍
- Chromatin and epigenetic regulation in ground state pluripotency🔍
- Targeting SERCA2 in organotypic epidermis reveals MEK inhibition ...🔍
Epigenetic modifications driving ground state pluripotency exit ...
transcriptional changes during exit from the naïve state ... rapid genome-wide demethylation to the epigenetic ground state of pluripotency.
Chromatin and Epigenetic Rearrangements in Embryonic Stem Cell ...
Cells grown in 2iLIF also have an altered chromatin state and reduced levels of repressive marks; for example, H3K27me3 levels are reduced at developmental ...
Wandering along the epigenetic timeline
It has been shown that DNA and histones can undergo chemical modifications such as methylation and acetylation—for histones only—that will guide ...
Catenin and Activating TCFs Reconstitutes Ground State ...
drive ground state pluripotency. Recently, inhibitor cocktails ... Exit from pluripotency is gated by intracellular redistribution of ...
Stem Cell Epigenetics: Insights from Studies on Embryonic, Induced ...
A recent study of spermatogonial stem cells showed dynamic epigenetic changes occur during differentiation, suggesting that, in both embryonic- ...
Otx2 and Oct4 drive early enhancer activation during embryonic ...
Pluripotency state transition of embryonic stem cells requires the turnover of histone chaperone FACT on chromatin. ... Articles in the Open Access Subset are ...
Chromatin and epigenetic regulation in ground state pluripotency
1.2 Chromatin and epigenetic modifications ... dependent changes of specific ground state chromatin conformation. ... Required for Exit from Pluripotency in ESCs.
Targeting SERCA2 in organotypic epidermis reveals MEK inhibition ...
Epigenetic modifications driving ground state pluripotency exit require an NF-κB-independent chromatin IκBα function by PaperPlayer biorxiv cell biology. 20 ...
Luis G. Palma on X: "Very happy to have the first version of the ...
Epigenetic modifications driving ground state pluripotency exit require an NF-κB-independent chromatin IκBα function https://biorxiv.org/cgi/content/short ...
Epigenetic mechanisms including histone modifications and DNA ... tion to the epigenetic ground state of pluripotency. Cell Stem Cell.
Vincent Pasque - Stamcelinstituut Leuven (SCIL) - KU Leuven
Epigenetic reprogramming, which remodels many epigenetic modifications, is important for at least three major biological processes: 1) obtaining pluripotent ...
Reprogramming of DPSC to Induced Pluripotent Stem Cells
In 2006, a breakthrough in understanding the main regulators of the ESC state occurred when Shinya Yamanaka and colleagues demonstrated that a ...
Epigenetic regulation of human naïve pluripotency - YouTube
Comments · PSCs to Cardiomyocytes in Three Steps · Synthetic Ex Utero Embryogenesis: From Naive Pluripotency to Stem-Cell Derived Embryo Models.
Epigenetic regulation of pluripotency and differentiation. – CIRM
Not only do epigenetic mechanisms regulate transcriptional states in a cell-type-specific manner but also they establish higher order genomic topology and ...
Paul Andersen explains the concepts of genetics. He starts with a brief discussion of the nature vs. nurture debate and shows how ...
What role do epigenetic modifications play in maintaining stem cell ...
What role do epigenetic modifications play in maintaining stem cell pluripotency during developmental stages of embryo development? ... Methylation of specific ...