- The IBD BioResource Protocol Version 6🔍
- Understanding Inflammatory Bowel Disease using High|Throughput ...🔍
- Inflammatory Bowel Disease 🔍
- Insights into the genetic epidemiology of Crohn's and rare diseases ...🔍
- The genetics of Crohn's disease and ulcerative colitis🔍
- Largest ever study of genetics of common diseases published today🔍
- Genome‐wide association studies in Crohn's disease🔍
- Enhanced microbiota profiling in patients with quiescent Crohn's ...🔍
Large sequencing effort links new genes to Crohn's disease risk
The discovery of genes that influence risk of IBD and how the disease behaves, ... large sample sizes) – and an assessment of gene-environment interactions.
Understanding Inflammatory Bowel Disease using High-Throughput ...
I then test for novel IBD associations in a low coverage whole genome sequencing dataset, and uncover a significant burden of rare, damaging missense variation ...
Inflammatory Bowel Disease (IBD) Research Study - 23andMe
We believe DNA may play a critical role in IBD treatment. Genetics has started playing a larger role in medicine over the past few years. And genetics could ...
Insights into the genetic epidemiology of Crohn's and rare diseases ...
... sequence variants to the risk and prevalence of Crohn's disease (CD) and rare diseases in the Ashkenazi Jewish (AJ) population. Genetic ...
The genetics of Crohn's disease and ulcerative colitis
risk loci employing large and dense array data sets. ... emphasizes that large-scale whole genome sequencing efforts are urgently needed.
Largest ever study of genetics of common diseases published today
Four new chromosome regions have been confirmed to increase the risk of developing this autoimmune disease, and two further possible regions ...
Genome‐wide association studies in Crohn's disease: Past, present ...
However, genetic studies in CD were not always successful. Initial efforts to identify the genetic determinants of CD were performed using ...
Enhanced microbiota profiling in patients with quiescent Crohn's ...
Prior studies indicate no correlation between the gut microbes of healthy first-degree relatives (HFDRs) of patients with Crohn's disease (CD) and the ...
The Human Genome Is the Future of Healthcare - Johnson & Johnson
The company's partnership with the largest human genome sequencing project in the world will increase scientists' understanding of genetic diseases and help ...
Inflammatory Bowel Disease Genetic Risk Architecture Appears ...
Using whole-genome sequence data for thousands of African American individuals, researchers teased out ancestry effects on polygenic risk of ...
New Insights into Genetics of Crohn's Disease Could Help Non ...
Mount Sinai research shows how known genetic mutations can cause Crohn's disease and also highlights a possible new treatment for patients who don't respond to ...
Interpretation of gene expression data to tackle inflammatory bowel ...
An analysis of samples retrieved from 19 patients and six healthy controls revealed 350 alternative splicing events spanning more than 240 genes. A deeper dive ...
Genetics and phenotypes in inflammatory bowel disease - The Lancet
Beginning with the early linkage studies, and continuing through identification of the NOD2 gene until the most recent era of genome-wide ...
Genetic Risk Profiling and Prediction of Disease Course in Crohn's ...
Homozygosity for the rs1363670 G-allele in a gene encoding a hypothetical protein near the IL12B gene was independently associated with ...
LRRK2 is a member of the leucine-rich repeat kinase family. Variants of this gene are associated with an increased risk of Parkinson's disease and Crohn's ...
Gut Microbiota and Immune System Dynamics in Parkinson&rsquo
Dysbiosis of the gut microbiota has been implicated in numerous disorders, ranging from intestinal diseases, such as colorectal cancer and inflammatory bowel ...
Live Science | Latest science news and articles for those with ...
Daily discoveries, groundbreaking research and fascinating science breakthroughs that impact you and the wider world, reported by our expert journalists.
Careers & Job Opportunities - SickKids
We work to determine the role genes play in paediatric health by innovating sequencing and disease modelling technologies. ... Working at SickKids means both new ...
Harnessing AI for advancing pathogenic microbiology: a bibliometric ...
AI's ability to analyze large volumes of genomic sequence data allows it to identify and compare genetic characteristics of diverse microorganisms, revealing ...
... high degree of both genetic and phenotypic diversity. Genome ... The "b" names were created after Fred Blattner, who led the genome sequence effort.