Mechanisms of inflammasome activation

binding and activation mechanisms of the AIM2 inflammasome and IFI16 receptor. ... NLRP3 inflammasome activation by promoting Nrf2 antioxidant pathway. J ...

Inflammasome and Autophagy Regulation: A Two-way Street

Although the underlying mechanisms of autophagy regulation of caspase-11 activation remain largely unclear, it is may be that autophagy inhibits ...

Mechanisms of Inflammasome Inhibition by Salmonella

Inflammasome activation plays a key role in host defense against diverse pathogens, but a number of bacterial and viral pathogens have recently been found to ...

Functional degradation: A mechanism of NLRP1 inflammasome ...

The NLRP1B inflammasome is activated upon direct cleavage by the anthrax lethal toxin protease. However, the mechanism by which cleavage results in NLRP1B ...

Mechanisms of inflammasome activation by Vibrio cholerae ...

Activation of inflammasomes is an important aspect of innate immune responses to bacterial infection. Recent studies have linked Vibrio cholerae secreted ...

New Insights on NLRP3 Inflammasome: Mechanisms of Activation ...

This review gives an overview of the established NLRP3 inflammasome assembly, its brief molecular mechanistic activations as well as a current update on ...

Spectrum and Mechanisms of Inflammasome Activation by Chitosan

Chitosan induced significant IL-18 and IL-1β responses, activating the inflammasome of a broad range of cell populations and across species, ...

Mechanisms of inflammasome activation: recent advances and ...

Inflammasomes are cytosolic multiprotein platforms as- sembled in response to invading pathogens and other danger signals. Typically inflammasome complexes ...

NLRP3 Inflammasome Activation - Promega Corporation

The inflammasome pathway is a crucial component of the innate immune system, the body's first line of defense against pathogens and harmful substances. The ...

The Inflammasome - YouTube

When you get a bacterial infection, the immune response needs to be very rapid. But it can take hours to sense a threat, and generating ...

Mechanisms of inflammasome activation: recent advances and ...

Inflammasomes are cytosolic multiprotein platforms assembled in response to invading pathogens and other danger signals. Typically inflammasome ...

Mechanisms of inflammasome activation: recent advances and ...

RNA viruses promote activation of the NLRP3 inflammasome through a RIP1-RIP3-DRP1 signaling pathway. ... Inflammatory caspases are innate immune receptors for ...

Exploiting Mass Spectrometry to Unlock the Mechanism of ...

In a recent study, inflammasome activation was suggested to occur in a single supramolecular structure that coincides with the microtubule- ...

Interrogating NLRP3 inflammasome activation mechanisms | Eucor EN

The NLRP3 inflammasome is involved in host defence against cancer and infection, but is also a major instigator of pathological inflammation in several ...

HDAC6 mediates an aggresome-like mechanism for NLRP3 and ...

They initiate both the maturation of inflammatory cytokines and pyroptosis, a type of programmed cell death. One notable feature for inflammasome activation is ...

Toward a Unified Model for Caspase Activation by Inflammasomes

We also examine mechanisms of caspase substrate selection and how inflammasome and cell identities influence caspase activity and resultant ...

The inflammasome signalling pathway updated - YouTube

University of Queensland Institute for Molecular Bioscience researcher Professor Kate Schroder explains the signal transduction pathway of ...

Predicting Multi-Interfacial Binding Mechanisms of NLRP3 and ASC ...

The inflammasomes are multiprotein complexes that serve as molecular platforms to activate pro-caspase-1 and other caspases and regulate the ...

Molecular mechanism for NLRP6 inflammasome assembly ... - PNAS

Inflammasomes are large protein complexes that trigger host defense in cells by activating inflammatory caspases for cytokine maturation and ...

What is an inflammasome? - YouTube

When the body senses danger, key proteins assemble into the inflammasome to fight injury and infection through inflammation.