Mendelian randomization analyses clarify the effects of height on ...

The causal effects of education on adult health, mortality and income

Here we compare two natural experiments: a policy reform, raising the school leaving age in the UK in 1972; and Mendelian randomization. METHODS ...

Instrumental Heterogeneity in Sex-Specific Two-Sample Mendelian ...

... explain the possible consequence in real data analysis. ... Causal effects of blood lipids on amyotrophic lateral sclerosis: a Mendelian randomization study.

Using Mendelian randomization to determine causal effects of ...

We recommend a set of analyses that ought to be considered when MR is used to address research questions concerned with intrauterine effects on ...

Mendelian randomization: Using genes as instruments for making ...

Illustration of IV analysis of the effect of CRP on HOMA-R score using diplotype (haplotype ... Section 2, for pleiotropy to explain the lack of ...

Overview of Mendelian Randomization Analysis

MR can provide more credible estimates of the causal effect of a risk factor on an outcome than those obtained in observational studies by ...

Intergenerational (or dynastic) effects - MR Dictionary

Nuesch E, Dale C, Palmer TM et al. Adult height, coronary heart disease and stroke: a multi-locus Mendelian randomization meta-analysis. Int J Epidemiol 2015; ...

Basic Concepts of a Mendelian Randomization Approach

Genetic risk score (GRS) is used to enhance the quantitative effect of IVs on risk factors. GRS analysis is based on SNPs selected from genetic ...

Ronald Fisher - Wikipedia

Sir Ronald Aylmer Fisher FRS (17 February 1890 – 29 July 1962) was a British polymath who was active as a mathematician, statistician, biologist, ...