Researchers Target a Major Hurdle for Retinal Stem Cell Replacement

Australian scientists conduct stem cell research unveiling a detailed ...

According to a news release from the University of Melbourne, by comparing stem cell models of the retinal ganglion cells of people with Primary ...

Stem Cell Research Fund - Maryland State Archives

Disease Target: Acute Respiratory Distress syndrome (ARDS). Stem cell therapy holds great promise in medicine, but faces hurdles to define basic parameters ...

A stem cell journey in ophthalmology: From the bench to the clinic

Luxturna is the first approved gene therapy for an inherited retinal disease and the first adeno-associated virus vector gene therapy approved ...

Research - CureCHM

The CRF has partnered with 4D Therapeutics to create a novel CHM gene therapy vector that could have the potential to reach more retinal cells ...

Autologous Adipose Tissue Stem Cell-Derived Terminally ...

Several strategies aim to prevent the RPE degeneration by saving the damaged retinal cells or replacing them. Cell rescue provides retinal cells with trophic or ...

Recent Progress in Photoreceptor Cell-Based Therapy for ...

Age-related macular degeneration and retinitis pigmentosa are degenerative retinal diseases that cause severe vision loss. Early clinical trials ...

Single-cell transcriptomics reveals maturation of transplanted stem ...

Transplantation of stem cell–derived retinal pigment epithelial (RPE) cells is considered a viable therapeutic option for age-related macular ...

Stem cell therapy in retinal diseases - Neural Regeneration Research

In the vast majority of human clinical trials, retinal pigment epithelial cells and photoreceptors are the cell types considered for replacement cell therapies.

a noninvasive AI approach to clinical release testing - JCI

In 2004, Haruta et al. published one of the earliest studies demonstrating the generation of RPE cells from primate embryonic stem cells (ESCs), ...

Stem Cell Therapies in Clinical Trials: Progress and Challenges

We also considered placental-derived stem cells that are frequently MSC-like and endothelial stem or progenitor cells because of their close relationship to ...

Scientific Grants and Awards Programs

Objective: To restore sight after photoreceptor loss by strategies to rescue or replace degenerating or dead retinal cells, optimize visual prostheses, and ...

Progress towards a stem cell-based therapy for blindness

Scientists are developing an effective stem cell-based therapy to regenerate photoreceptors cells and restore sight in people with blindness.

Did Surgeons Just Transplant a Whole Eye?

Though research is being done in preclinical animal models to study the role of stem cells as a treatment for several eye diseases, there is no ...

Stem cell therapies for retinal diseases: recapitulating development ...

Retinal degenerative diseases are the leading causes of blindness worldwide. Replacing lost retinal cells via stem cell-based therapies is ...

Stem Cell Therapy News - Usher Syndrome Coalition

Researchers used stem cells from an individual with retinitis pigmentosa (RP) caused by mutations in their USH2A gene to create retinal organoids (ROs), that ...

So Doc, What About Stem Cells? The Potential of Stem Cells in ...

Unfortunately, RPE transplantation alone is likely not enough to restore visual function in the stem cell-mediated treatment of AMD. Photoreceptor dysfunction ...

Cell therapy—unlocking groundbreaking potential | Astellas Pharma ...

Astellas is conducting a clinical trial in the field of ophthalmology in a retinal pigment epithelial cell program for treating geographic ...

Stem Cell Revolution: Regenerating the Eye

“One of the things that's unique to an embryonic stem cell is that when you first derive it, it's fetal tissue,” he says. “So the RPE cells we ...

Gamm Lab – Waisman Center – UW–Madison

The expansion and targeted differentiation of human stem and progenitor cells in vitro provide an essential source of biological material for modeling retinal ...

Stem cell growth | Sigma-Aldrich

Peng Wang et al. Stem cell research & therapy, 8(1), 114-114 (2017-05-18). Basic fibroblast growth factor (bFGF) plays an important role in promoting wound ...