Sequence and structural conservation reveal fingerprint residues in ...

Sequence and structural patterns detected in entangled proteins ...

Thus, we expect to detect a related fingerprint in the specific amino acids found in contact with each other at the end of entangled loops. (“entangled ...

Examples

Binding sites predictions were obtained by calculating the structural conservation scores for the query protein residues based on these retrieved structures. We ...

Structure-based prediction of ligand–protein interactions on a ...

of protein structural alignment to detect ... protein ligand binding sites by combining evolutionary sequence conservation and 3D structure.

Structure, Evolutionary Conservation, and Conformational Dynamics ...

The structure reveals a novel arrangement of four tandem β-trefoil ... Sequence conservation analysis confirms the importance of hydrophobic core residues ...

‪Daniele Granata‬ - ‪Google Scholar‬

Sequence and structural conservation reveal fingerprint residues in TRP channels. D Cabezas-Bratesco, FA Mcgee, CK Colenso, K Zavala, D Granata, ... Elife 11 ...

Identification of functionally conserved residues with the use of ...

Aiming at a method for harvesting the wealth of informa- tion present in sequence (and structure) data, we analyzed conservation patterns in multiple-sequence ...

Latent Print Development - Office of Justice Programs

Latent prints on these substrates are more susceptible to damage because the fingerprint residue resides on the out- ermost surface. Cyanoacrylate (CA), dye ...

Excavating the functionally crucial active-site residues of the DXS ...

... conservation score in 4 sequences, including the reference protein structure. Within the reference structure, motifs 1 and 3 are orderly ...

Evolution of Sequence and Structure of SARS-CoV-2 Spike Protein

These analyses show that by grouping related variants, the genomic sequences of SARS-CoV-2 may be effectively used to capture the lineage ...

The structure of a major surface antigen SAG19 from Eimeria tenella ...

Furthermore, sequence comparisons show that the Eimeria SAG fold is conserved in surface ... 2 Structural organisation of the conserved residues found ...

A structural study for the optimisation of functional motifs encoded in ...

the sequence positions of the structurally conserved residues falling outside the pattern are used to build extended sequence patterns. 3. the ...

BIOINFORMATICS ORIGINAL PAPER - Fred P. Davis

investigate properties such as residue type propensities, sequence conservation and structure conservation at protein interfaces (Valdar and Thornton, 2001 ...

Examples - SWISS-MODEL

The QSQE (Quaternary Structure Quality Estimation); The target–template sequence identity; The experimental method used to determine the structure (and ...

[PDF] In Silico Site-Directed Mutagenesis Informs Species-Specific ...

This study found that computationally derived substitutions in identities of key amino acids caused no change in protein-chemical interaction if residues ...

Sequence-structure analysis of FAD-containing proteins

4A). Conserved sequence motifs. The GR family members show several conserved amino ... residues in partially conserved sequence motifs. As a result, the ...

Secondary structure prediction from multiple sequence data: blood ...

The aligned protein tyrosine phosphatases show two regions (L39-L80 and I138-E253) with clear patterns of residue conservation separated by a region of variable ...

Single-Sequence-Based Protein Secondary Structure Prediction ...

In this study, we developed two novel chemical representations for amino acids utilizing molecular fingerprints and the dimensionality reduction algorithm ...

Conservation, Evolutionary - Proteopedia, life in 3D

Locating Conserved Patches. Patches of highly conserved amino acid residues on the surface of a protein molecular structure are good candidates for functional ...

Sequence Fingerprints of MicroRNA Conservation | PLOS ONE

We further revealed that the non-U preference at the 5′ end of less-conserved mammalian miRNAs is associated with miRNA function diversity, which may have ...

structure-based approach to protein function prediction - CiteSeerX

Here, the use of functionally discrimi- nating residues that act as a filter once a sequence is assigned as being evolutionary related to ...