Spatial control of membrane receptor function using ligand ...

Spatial organization-dependent EphA2 transcriptional responses ...

... receptors, which confirmed receptor binding to the ligands ... (2014) Spatial control of membrane receptor function using ligand nanocalipers.

Ligand entry pathways control the chemical space recognized by ...

The G protein-coupled receptor GPR183 is a chemotactic receptor with an important function in the immune system and association with a ...

Special Issue : Structure and Function of Membrane Receptors - MDPI

These endocytic receptors bind specific ligands and, through invagination of the cell membrane, the ligands are imported into the interior of the cell. This ...

‪Alan Shaw‬ - ‪Google Scholar‬

Spatial control of membrane receptor function using ligand nanocalipers. A Shaw, V Lundin, E Petrova, F Fördős, E Benson, A Al-Amin, A Herland, ... Nature ...

Rafts and synapses in the spatial organization of immune cell ...

The ligand-binding chains are integral membrane pro- teins with small intracellular domains that have no inherent kinase activity and are themselves inert with ...

Structure, function, and allosteric modulation of NMDA receptors

There is a rapidly increasing body of data from crystal or cryo-EM structures of intact NMDA receptors or individual domains, which provides a structural ...

Spatial control of ligand presentation on biomaterial surfaces

Adhesion of many cell types to the extracellular matrix or to synthetic bioactive surfaces is mediated by transmembrane integrin receptors.

Mechanisms of Notch signaling: a simple logic deployed in time and ...

Receptors in a given cell are activated in a juxtacrine manner by cell surface ligands from neighboring cells in a process known as 'trans- ...

9.1 Signaling Molecules and Cellular Receptors - Biology 2e

... membrane allow for the controlled flow ... ligands can directly diffuse through the plasma membrane and interact with internal receptors.

General principles of binding between cell surface receptors ... - PLOS

The interactions between membrane receptors and extracellular ligands control cell-cell and cell-substrate adhesion, and environmental responsiveness by ...

Macrophage activation on “phagocytic synapse” arrays: Spacing of ...

Our study demonstrates the feasibility of using spatially patterned ligands to modulate innate immunity. It shows that the receptor clusters of ...

SpatialDM: Rapid identification of spatially co-expressed ligand ...

... with 0% variance explained by ligand-receptor spatial interaction. ... : Deciphering tissue structure and function using spatial transcriptomics.

Significance of Receptor Mobility in Multivalent Binding on Lipid ...

In particular, membrane mobility is often relevant for multivalent interactions, where a ligand with multiple binding sites engages a number of ...

28.2: At the cell membrane- receptors and receptor enzymes

We have already discussed integral and peripheral membrane proteins in Chapter 11. When occupied by a ligand signal, the signaling event ...

Applications and analytical tools of cell communication based on ...

With the increasing discovery on receptors and ligands and their interactions, compilation by sorting and summarizing relevant information into ...

Ligand | Definition, Examples & Properties - Lesson - Study.com

Ligands for intracellular receptors must have specific properties to be able to pass through the cell membrane. First, they must be mostly hydrophobic, meaning ...

Full control of ligand positioning reveals spatial thresholds for T cell ...

Elucidating the rules for receptor triggering in cell-cell and cell-matrix contacts requires precise control of ligand positioning in three dimensions.

Cell Membrane Receptors - GLOWM

Hormone receptors in this group function as ligand-gated ion channels and belong to a family of homologous, multipass transmembrane proteins (Fig. 4). Channel- ...

Measuring ligand-cell surface receptor affinities with axial line ... - eLife

In multicellular organisms, cell-cell communication is mediated to a large extent by cell surface receptors in the plasma membrane. They bind ...

A Spatial Look at Cell-Cell Interactions - NanoString

While spatially proximal, direct ligand-receptor interactions often involve different cell types that can be differentiated by spatial multiomic ...