Therapeutic applications of germline testing for cancer ...

when somatic tumour testing and germline mutations meet - Nature

There is no question that these tests have provided clinical benefit to the patient and her/his family. However, with the expanding role of next ...

All colorectal cancer patients require germline testing at diagnosis ...

The genetic fingerprinting of individual tumors has fueled the development of targeted therapies and informed their appropriate deployment for ...

Genetic Counseling and Germline Testing in the Era of Tumor ...

The clinical impact of addressing potential germline alterations from tumor-only next-generation sequencing (NGS) is not well characterized.

Understanding Genetic Testing for Cancer Risk

Genetic testing is the use of medical tests to look for certain mutations (changes) in a person's genes.

Ed Esplin on LinkedIn: Therapeutic applications of germline testing ...

1/3 of #cancer #patients w/ #genetictesting in an Asian tertiary centre carried a #germline PGV. ~75% of advanced #cancer #patients w/ ...

Guidelines on Genetic Testing in Cancer Patients

The American Society of Clinical Oncology (ASCO) recently released guidelines on germline genetic testing in patients with cancer.

Hereditary Cancer Testing 2024-06-30 updated 10-01

The ESMO and ACG guidelines for hereditary gastrointestinal cancers use a lower threshold for germline genetic testing recommending that patients with multiple ...

Clinical Impact of a Rapid Genetic Testing Model for Advanced ...

Oncologist-initiated germline genetic testing in collaboration with a genetic counselor is a feasible approach to testing advanced prostate ...

Broad-based testing increases detection of inherited germline ...

Mayo Clinic researchers studying germline genetic alterations among patients with solid tumor cancer found that universal multigene panel ...

Clinical Cancer Genomics Research Program - City of Hope

This study will enable patients to opt in to no-cost germline genetic testing for >150 cancer genes and 34 non-cancer genes and, in some cases, includes tumor ...

Limited Independent Follow-Up with Germline Testing of Variants ...

Genomic profiling is performed in patients with advanced or metastatic cancer, in order to direct cancer treatment, often sequencing ...

FoundationOne CDx | Foundation Medicine

The test is designed to provide physicians with clinically actionable information - both to consider appropriate therapies for patients and understand results ...

How and When to Consider Genetic Testing for Colon Cancer?

Genetic testing would be offered to patients who meet the clinical criteria for a particular hereditary cancer syndrome. This finding led to germline testing of ...

ESMO Recommendations on clinical reporting of genomic test ...

Genomic tumour profiling has a crucial role in the management of patients with solid cancers, as it helps selecting and prioritising ...

New ASCO guidelines for germline genetic testing in patients with ...

Determining whether a cancer is due to a germline mutation can help in guiding therapeutic decisions, as well as in early detection of ...

Billing and Coding: Germline testing for use of PARP inhibitors - CMS

Article Guidance · The patient meets clinical indication for immediate use of a PARP inhibitor for an FDA-approved use AND · The patient has had no previous ...

Enhanced Clinical Education and Simplified Guidelines Needed to ...

Although the use of precision oncology has transformed breast cancer management, there is a notable under-utilization of germline testing in ...

MyRisk® Germline Test for Cancer Treatment - Myriad Genetics

NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines®) recommend germline testing in the workup for patients diagnosed with, or after confirmation of, ...

Hereditary Cancer Syndromes and Risk Assessment - ACOG

These tests also require expertise and context for clinical application. It ... somatic cells, hereditary cancer syndromes are attributable to germline testing ...

Racial Disparity Seen in Use of Germline Testing in TNBC

The study explored the use of germline testing of women with triple-negative breast cancer (TNBC) who were patients in US Oncology Network ...