Using Circulating Tumor DNA in Colorectal Cancer

Circulating tumor DNA (ctDNA) serial analysis during progression ...

Blood-based biomarkers such as carcinoembryonic antigen and CA 19-9 were employed to assess treatment response and monitor disease progression along with ...

Circulating Tumor DNA in Precision Oncology and Its Applications in ...

The general aspects of ctDNA are examined, including its status as a biomarker, and its role in the management of early (II–III) and late (IV; ...

Postoperative circulating tumor DNA detection is associated with the ...

Circulating tumor DNA (ctDNA) is reported to be promising in localized colorectal cancer (CRC). The present study aimed to retrospectively evaluate the ...

Circulating Tumor DNA in Stage III Colorectal Cancer, beyond ...

Treatment of ctDNA-positive patients with standard adjuvant therapy prevented recurrence in only 20% of patients. Accordingly, further studies ...

Mutational Profiling Using Circulating Tumor DNA Helps Guide ...

Circulating tumor DNA (ctDNA) has rapidly emerged as a promising dynamic biomarker to aid with clinical decision-making for CRC.

Presence of ctDNA Does Not Predict Benefit of Adjuvant ... - OncLive

Adjuvant chemotherapy did not improve circulating tumor DNA clearance in patients with stage II colon cancer with baseline circulating tumor ...

Use of Circulating Tumor DNA to Monitor Minimal Residual Disease ...

The emergence of molecular analysis approaches that use circulating tumor DNA (ctDNA) to measure minimal residual disease is shifting the ...

Circulating Tumor DNA in Colorectal Cancer—From Concept to Clinic

The advent of liquid biopsies, in the form of circulating tumor DNA (ctDNA), has many potential clinical applications including non-invasive ...

Predicting Recurrence in Colorectal Cancer Using Postoperative ...

Postoperative molecular residual disease detected by circulating tumor DNA (ctDNA) at 4 weeks after resection has emerged as the strongest ...

Circulating Tumor DNA Testing in Predicting Treatment for Patients ...

Testing for ctDNA levels may help identify patients with colon cancer who benefit from receiving chemotherapy after surgery. It is not yet known whether giving ...

Circulating Tumor DNA Guiding Adjuvant Therapy in Colon Cancer

Tie and colleagues (June 16 issue) reported that basing decisions regarding adjuvant chemotherapy in stage II colon cancer on the presence ...

Clinical utility of circulating tumor DNA for colorectal cancer - Osumi

Circulating tumor DNA (ctDNA) carrying tumor-specific genetic or epigenetic alterations is released into the circulation from tumor cells ...

Detection of circulating tumor DNA in patients of operative colorectal ...

Liquid biopsy is now an emerging approach for the precision oncology, through applications in the detection of cancer cells noninvasively and ...

Circulating tumor DNA analysis detects minimal residual disease ...

ctDNA detection after stage II colon cancer resection provides direct evidence of residual disease and identifies patients at very high risk of recurrence.

The potential of ctDNA in locoregional therapies for colorectal cancer

ctDNA could be used as an additional tool to judge the extent of disease before initiating local therapy (either neoadjuvantly or adjuvantly), which could help ...

Perlmutter Cancer Center Clinical Trial Aims to Use Circulating ...

This arm aims to determine if people with low risk stage 3 colon cancer and no ctDNA after surgery, whose cancer is not expected to recur, and ...

Impact of circulating tumor DNA early detection and serial ...

In the specific setting of stage I to III colorectal cancer (CRC), post-operative carcinoembryonic antigen (CEA) and carbohydrate antigen 19-9 (CA19-9) revealed ...

Postoperative circulating tumor DNA as markers of recurrence risk in ...

Colorectal cancer (CRC) is the third most common cancer around the world with more than 1.9 million new cases diagnosed annually [1]. CRC is ...

Circulating Tumor DNA Testing in Predicting Treatment for Patients ...

ctDNA are circulating tumor cells that are shed by tumors into the blood. Finding ctDNA in the blood means that there is very likely some small amounts of ...

Circulating tumor DNA: a new frontier in colorectal cancer - YouTube

Dr. Stacey Cohen of the University of Washington and Fred Hutchinson Cancer Research Center discusses circulating tumor DNA in this DocTalk, ...