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Cisplatin|Associated Nephrotoxic Effects in Children


Correlation of adverse effects of cisplatin administration in patients ...

Among the negative side effects with a more or less severe involvement of tissues include neurotoxicity, nephrotoxicity and ototoxicity (2,13,25 ...

Persistent nephrotoxicity during 10-year follow-up after cisplatin or ...

Persistent nephrotoxicity during 10-year follow-up after cisplatin or carboplatin treatment in childhood: relevance of age and dose as risk factors. · 117 ...

Saving Ears and Kidneys from Cisplatin - Anticancer Research

Cisplatin Toxicities. The main side-effects of cisplatin treatment are nephrotoxicity, which is often dose-limiting, ototoxicity, and neurotoxicity. In patients ...

Toxic environmental exposures and kidney health in children.

High-level exposures to a number of agents are known to have direct nephrotoxic effects in children. A growing body of literature supports the ...

TNF-α mediates chemokine and cytokine expression and renal ... - JCI

To confirm that the effects of these agents on cisplatin nephrotoxicity were mediated through TNF-α, we used mice in which the TNF-α gene had been genetically ...

Nephrotoxicity of anticancer treatment - Oxford Academic

The most nephrotoxic chemotherapeutic drug is cisplatin, which is often associated with acute kidney injury. Many other drugs such as alkylating ...

Cisplatin Induced Kidney Toxicity - ClinicalTrials.Veeva

Nephrotoxicity is one of the most common adverse effects of CisP, occurring in 20-50% of patients. It manifests as acute kidney injury (AKI) ...

The Effect of Vitamin E on Cisplatin Induced Nephrotoxicity

Background Cisplatin is a common platinum based chemotherapy drug that is commonly used for the treatment of the solid tumors. It is believed that this drug ...

Cisplatin dosing, indications, interactions, adverse effects, and more

Adverse Effects · >10%. Nausea (76-100%). Vomiting (76-100%). Nephrotoxicity (28-36%). Ototoxicity, especially in children (31%). Myelosuppression (25-30%).

Activation and involvement of p53 in cisplatin-induced nephrotoxicity

Cisplatin, a widely used chemotherapy drug, induces acute kidney injury, which limits its use and efficacy in cancer treatment.

Nephrotic syndrome - Symptoms & causes - Mayo Clinic

... kidney-disease/children/childhood-nephrotic-syndrome. Accessed Nov. 22, 2019 ... Associated Procedures. Kidney biopsy · Urinalysis. Products & Services. A ...

Acute kidney injury - Symptoms and causes - Mayo Clinic

Older age, but it does happen to children. Being in the hospital ... Show more associated procedures. Products & Services. A Book: Mayo ...

Creatine Information | Mount Sinai - New York

Side effects of creatine include: Weight gain; Muscle cramps; Muscle strains and pulls; Stomach upset; Diarrhea; Dizziness; High blood pressure; Liver ...

Understanding your lab values and other CKD health numbers

You may also need extra tests to monitor for other health conditions that are related to kidney disease. ... children for protein in their urine, your ...

Furosemide: Side effects, dosage, uses, and more

It's also used to treat edema in adults and some children, which is swelling caused by fluid buildup in your body. Important warnings. FDA warning: Dehydration ...

Herpes - STI Treatment Guidelines - CDC

Persons with HSV-1 antibodies often have oral HSV infection acquired during childhood, which might be asymptomatic. Lack of symptoms in a person who is HSV-1 ...

Flucloxacillin | Drugs | BNF - NICE

Side-effects · Common or very common. Diarrhoea; hypersensitivity; nausea; skin reactions; thrombocytopenia; vomiting · Uncommon. Antibiotic associated colitis; ...

Co-amoxiclav | Drugs | BNF - NICE

Side-effects · Common or very common. Diarrhoea; hypersensitivity; nausea; skin reactions; thrombocytopenia; vomiting · Uncommon. Antibiotic associated colitis; ...

Aripiprazole - Wikipedia

Aripiprazole, sold under the brand names Abilify and Aristada, among others, is an atypical antipsychotic. It is primarily used in the treatment of ...

Clonidine: Uses, Dosage, Side Effects, Warnings - Drugs.com

... associated with additional efficacy. Comments: -The transdermal ... -Children 6 years and older. -Initial Onyda XR dose: 0.1 mg orally ...