Cisplatin|induced nephrotoxicity in childhood cancer

Renal and Hepatic Health After Childhood Cancer - Pediatric Clinics

Risk factors for long-term outcome of ifosfamide-induced nephrotoxicity in children ... ∙ Daugaard, G. Cisplatin and hypomagnesemia. Cancer ...

Nephrotoxicity of Cancer Treatment in Children

The cytotoxic drugs most likely to cause important chronic nephrotoxicity are ifosfamide and cisplatin, both of which are used widely in many solid tumors and ...

The ability of mannitol to decrease cisplatin-induced nephrotoxicity ...

Unfortunately, the risk of severe disabling effects such as nephrotoxicity is well known among children receiving cisplatin-based chemotherapy.

Relevance of age and d - European Journal of Cancer

CCSK, clear cell sarcoma of kidney. Table 2 – Grading of cisplatin nephrotoxicity in children.8. Nephrotoxicity grade. GFR. Mg. < ...

Nephrotoxicity of cisplatin combination chemotherapy in thoracic ...

analyzed data for 4684 cancer patients and found that elevated sCre levels were less sensitive than was decreased Cre clearance for detecting ...

Cisplatin-Induced Renal Injury Is Independently Mediated by OCT2 ...

The human organic cation transporter OCT2 is known to be involved in cellular accumulation of cisplatin and contributes to cisplatin-induced nephrotoxicity.

Urinary Beta-2-Microglobulin and Late Nephrotoxicity in Childhood ...

However, childhood cancer survivors (CCS) are at greater risk of experiencing many treatment-related adverse effects that substantially affect ...

Long-Term Tubular Dysfunction in Childhood Cancer Survivors

Cisplatin was associated with magnesium loss and a cumulative dose > 500 mg/m(2) with potassium and phosphate loss. Carboplatin cumulative dose > 2800 mg/m(2) ...

Prediction of Nephrotoxicity Associated With Cisplatin-Based ...

Cisplatin-based chemotherapy may induce nephrotoxicity. This study presents a random forest predictive model that identifies testicular cancer patients at risk ...

1) Study title Incidence of and Risk Factors for Late End Stage Renal ...

Given the relative infrequency of end stage renal disease in childhood cancer ... Cisplatin nephrotoxicity: A review. Am J Med Sci 334: 115–124, 2007. 6 ...

Magnesium supplementation therapy to prevent cisplatin-induced ...

The present study aimed to examine the effect of magnesium (Mg) supplementation on cisplatin-induced nephrotoxicity (CIN) in pediatric cancer ...

Hypertension in long-term childhood cancer survivors after treatment ...

Persistent nephrotoxicity during 10-year follow-up after cisplatin or carboplatin treatment in childhood: relevance of age and dose as risk factors. Eur J ...

Nephrotoxicity of platinum derivatives in children - Termedia

Cancer and antineoplastic treatment are interrelated with the risk of injuring various tissues and organs, kidneys included. Nephrotoxicity is ...

Nephrotoxicity of Cancer Treatment in Children - Medscape

Abstract and Introduction · Epidemiology of Nephrotoxicity in Children with Cancer · Importance of Nephrotoxicity · Etiology · Nephrotoxicity Due to Specific ...

Risk factors for ifosfamide nephrotoxicity in children - The Lancet

Risk factors for long-term nephrotoxicity after ifosfamide for childhood cancers are not fully known. We have studied patient-related and treatment-related risk ...

MILK THISTLE: Overview, Uses, Side Effects, Precautions ... - WebMD

Kidney damage caused by cancer drugs. Early research shows that taking milk thistle extract beginning 24-48 hours before starting therapy with cisplatin, and ...

Publications

Axillary Ultrasound Assessment in Patients with Newly Diagnosed Primary Breast Cancer CA5118 v6 ... Induced Nephrotoxicity CIN v7 · Guideline for the Antibiotic ...