Cisplatin Toxicity in Children with Malignancy

Intravenous N-Acetylcysteine to Prevent Cisplatin-Induced Hearing ...

1Cancer and Blood Disease Institute, Children's Hospital Los Angeles, Los Angeles, California. 2Department of Pediatrics, Keck School of ...

Effect of n-acetylcysteine on cisplatin toxicity | BTT

The most common are nephrotoxicity, ototoxicity, neurotoxicity, gastrointestinal toxicity, and hematological toxicity. While less frequent, ...

Cisplatin | Cancer information - Cancer Research UK

Cisplatin is a type of chemotherapy. It is a treatment for a number of different types of cancer. Find out about how you have it, possible side effects and ...

Cisplatin dose rate as a risk factor for nephrotoxicity in children.

Follow-up studies revealed partial recovery of GFR (P < 0.05). Glomerular and proximal nephron toxicity are common in children treated with cisplatin, and more ...

Hearing Loss in Children with Hepatoblastoma - YouTube

Cisplatin is part of standard therapy for hepatoblastoma, a rare liver cancer, but hearing loss is a serious and permanent side effect.

Cisplatin Injection: MedlinePlus Drug Information

Hearing loss may be permanent in some cases. Your doctor will order tests to monitor your hearing before and during your treatment. Tell your ...

Medical interventions for the prevention of platinum‐induced ...

Platinum‐based therapy, including cisplatin, carboplatin, oxaliplatin or a combination of these, is used to treat a variety of paediatric ...

Prediction of Nephrotoxicity Associated With Cisplatin-Based ...

Cisplatin-based chemotherapy may induce nephrotoxicity. This study presents a random forest predictive model that identifies testicular cancer ...

Responses and adverse effects of carboplatin-based chemotherapy ...

... toxicities of risk-adapted chemotherapy in pediatric intracranial germ cell tumors. Korean J Pediatr 2005;48:186–190. 8. Yoo KH, Lee SH, Lee ...

New drug will prevent children with cancer from losing their hearing

Cisplatin is a powerful chemotherapy medicine used to treat many cancers in children. Over time, cisplatin builds up in the cochlea in the ...

Cisplatin and Combination Chemotherapy in Treating Children and ...

To reduce therapy associated toxicity for patients with non-metastatic hepatoblastoma (HB) and hepatocellular carcinoma (HCC) without adversely affecting long ...

Cisplatin (intravenous route) - Mayo Clinic

Appropriate studies have not been performed on the relationship of age to the effects of cisplatin injection in the pediatric population. Safety ...

Cisplatin - OUCI

Platinum Drugs in Children with Cancer · Early and late renal adverse effects after potentially nephrotoxic treatment for childhood cancer · Cisplatin Toxicity in ...

Chart Review of Predisposing Factors to Cisplatin-Induced ...

Cisplatin-induced nephrotoxicity is a major dose-limiting adverse event associated with the drug that can occur despite preventive measures. According to Miller ...

Correlation of adverse effects of cisplatin administration in patients ...

It is employed in children for treatment of haematological tumours and in adults for treatment of solid tumours such as testicular (2), prostatic and ovarian (3 ...

(PDF) Cisplatin dose rate as a risk factor for nephrotoxicity in children

Follow-up studies revealed partial recovery of GFR (P < 0.05). Glomerular and proximal nephron toxicity are common in children treated with cisplatin, and more ...

Effects of chemotherapy on the auditory system of children ... - SciELO

there is evidence that both carboplatin and especially cisplatin from the first doses may impair the hearing of children and adolescents, mainly affecting the ...

Evaluation of kidney dysfunction in childhood cancer survivors

... childhood cancer survivors receiving chemotherapy as cisplatin ... Renal toxicity and chemotherapy in children with cancer. Br. J. Clin ...

Effects of sodium thiosulfate versus observation on development of ...

Predicting cisplatin ototoxicity in children: the influence of age and the cumulative dose. Eur J Cancer 2004;. 40: 2445–51. 9 Gurney JG ...

Genetic Variations and Cisplatin Nephrotoxicity: A Systematic Review

Despite its benefit in cancer therapy, cisplatin is also known for its adverse reactions, such as ototoxicity, neurotoxicity, emesis and nephrotoxicity (Percie ...