Citations to Human liver chimeric mice provide a model for hepatitis ...

Challenge Pools of Hepatitis C Virus Genotypes 1–6 Prototype Strains

Human liver-chimeric mice developed high-titer infections after inoculation with the challenge viruses of genotypes 1–6. Inoculation studies with different ...

Depicting Human Liver Biology and Diseases in Mice

Advancement in both bioengineering and cell biology of the liver led to the establishment of the first-generation humanized liver chimeric mouse (HLCM) model in ...

HHS Public Access

model and the human-mouse liver/immune system chimeric model of HBV replication and infection have been developed. These models should help us to understand the.

Analysis of Hepatitis C Virus Particle Heterogeneity in ...

HCV · Lipoprotein · Mouse Model · Human Liver Chimeric Mice. Abbreviations used in this paper. Alb-uPA (Albumin-urokinase plasminogen activator); apo ( ...

HBsAg-redirected T cells exhibit antiviral activity in HBV-infected ...

19. Bissig, K.-D. ∙ Wieland, S.F. ∙ Tran, P. ... Human liver chimeric mice provide a model for hepatitis B and C virus infection and treatment.

Hepatitis C virus kinetics by administration of pegylated interferon-α ...

Furthermore, we prepared four lines of chimeric mice having four different lots of human hepatocytes containing various single nucleotide polymorphisms (SNP) ...

Using Chimeric Mice with Humanized Livers to Predict ... - AVESİS

2010) have developed chimeric mice, in which mouse liver is ... References. Anderson S, Luffer-Atlas D, and ... (2010) Human liver chimeric mice provide a model for ...

An Experimental Mouse Model for Hepatitis C Virus - J-Stage

2. Bissig, K.D., Wieland, S.F., Tran, P., Isogawa, M., Le, T.T., Chisari, F.V., and Verma, I.M. 2010. Human liver chimeric mice provide a model for hepatitis B ...

Mouse models for hepatitis B virus research

... HBV replicon delivery systems, adeno-associated virus-mediated HBV replicon delivery systems, and human liver chimeric mouse models. These ...

Induction of Human-Specific Liver Fibrosis and M2-Like Macrophages

The humanized mouse model is a valuable platform in studying HBV infection, human immune response and liver diseases. Furthermore, results from this study ...

Hepatitis B Virus Particles Activate Toll‐Like Receptor 2... - Hepatology

Generation and Infection of Human Liver Chimeric Mice ... Animals were maintained under specific pathogen‐free conditions in accordance with institutional ...

Human Hepatocytes Can Repopulate Mouse Liver - Sage Journals

In the present study, mouse-human chimeric livers contained variable numbers of human hepatocytes as demonstrated by IHC with human-specific hepatocellular ...

Mouse models for hepatitis B virus research. - Abstract - Europe PMC

Human liver chimeric mouse models ... Since mice are not a natural host for HBV, it is not possible to study the entire infection process (from ...

Study of Hepatitis E Virus-4 Infection in Human Liver-Chimeric ...

Human liver-chimeric mice have greatly aided in ... Moreover, the immunodeficient nature of this mouse model does not allow ... Cite this. APA; Author ...

Towards a small animal model for hepatitis C | EMBO reports

The natural species tropism of HCV is, however, limited to humans and chimpanzees. Here, we discuss the prospects of developing a mouse model for HCV infection, ...

Hepatitis E Virus (HEV) Genotype 3 Infection of Human Liver ...

Hepatitis E Virus (HEV) Genotype 3 Infection of Human Liver Chimeric Mice as a Model for Chronic HEV Infection ... 72 Citations ... We use cookies to help provide ...

Human liver chimeric mice as a novel model for the study of hepatitis ...

Ibrahim, Ibrahim Mahmoud Sayed, et al. “Human Liver Chimeric Mice as a Novel Model for the Study of Hepatitis E Virus Infections.” Program and Abstract Book ...

Hepatitis E Virus (HEV) Genotype 3 Infection of Human Liver ...

Citations. Article. ; Hepatitis E Virus (HEV) Genotype 3 Infection of Human Liver Chimeric Mice as a Model for Chronic HEV Infection. ; van de Garde, Martijn ...

Humanized Liver Mouse Models for Translational Preclinical Research

Humanized liver mouse models are generated on suitable transgenic backgrounds that allow for the ablation of the endogenous mouse hepatocyte and accept the ...

A human liver chimeric mouse model for non-alcoholic fatty liver ...

Within the same chimeric liver, human hepatocytes developed pronounced steatosis while murine he- patocytes remained normal. Unbiased ...