- PDGF/PDGFR Signaling in Cardiovascular Disease🔍
- PDGFR dimer|specific activation🔍
- Identification and functional characterization of imatinib‐sensitive ...🔍
- Gene expression profiling of imatinib|treated and untreated human ...🔍
- PDGFR in PDGF|BB/PDGFR Signaling Pathway Does Orchestrates ...🔍
- Signaling by PDGFR in disease🔍
- Avapritinib Approved for GIST with PDGFRA Gene Alteration🔍
- Platelet|Derived Growth Factor 🔍
ETV6|PDGFRB and FIP1L1|PDGFRA stimulate human ...
PDGF/PDGFR Signaling in Cardiovascular Disease
In vitro and in vivo studies demonstrate that PDGF-C and PDGF-D stimulate ... A platelet factor stimulating human normal glial cells. Exp Cell Res ...
PDGFR dimer-specific activation, trafficking and downstream ...
Cells were seeded onto glass coverslips coated with 5 µg/mL human plasma fibronectin purified protein (EMD Millipore Corporation) at a density ...
Identification and functional characterization of imatinib‐sensitive ...
... activation of the PDGFRB fusion protein. In vitro functional analyses ... ETV6-PDGFRB and FIP1L1-PDGFRA stimulate human hematopoietic ...
Gene expression profiling of imatinib-treated and untreated human ...
... PDGFR inhibitor, to switch off TEL-PDGFRb signaling. PubMed ID. 22271894. Publication Title. ETV6-PDGFRB and FIP1L1-PDGFRA stimulate human hematopoietic ...
PDGF isoforms stimulate proliferation, survival and motility of connective ... Human Mouse Rat, Human Mouse, Cow Dog Goat Chicken Cat Human Mouse Rat
PDGFR in PDGF-BB/PDGFR Signaling Pathway Does Orchestrates ...
... stimulate recruitment and proliferation of ... To go or not to go: Migration of human mesenchymal progenitor cells stimulated by isoforms of PDGF.
Signaling by PDGFR in disease - Reactome Pathway Database
PDGFRA and PDGFRB are type III receptor tyrosine kinases that promote ... Aberrant signaling through PDGF receptors is implicated in a number of human diseases.
Avapritinib Approved for GIST with PDGFRA Gene Alteration - NCI
“A PDGFR [exon 18] ... U.S. Department of Health and Human Services National Institutes of Health National Cancer Institute USA.gov.
Platelet-Derived Growth Factor (PDGF)/PDGF Receptors (PDGFR ...
In the last two decades, it was shown that PDGF and PDGFR are involved in human cancer development and progression through autocrine stimulation of tumor cell ...
Human PDGF R alpha / PDGFRA Protein, His Tag - ACROBiosystems
... PDGFRB under hypoxic conditions, and PDGFRB regulated the actin cytoskeleton, a process likely linked to the activation of RhoA and the phosphorylation of ...
... ETV6-PDGFRA (Gleich and Leiferman, 2009). The involvement of FIP1L1 ... Structure, organization, and transcription units of the human alpha- ...
Platelet-Derived Growth Factor Receptor-α Regulates Proliferation ...
PDGFRA signaling has been proposed to stimulate growth of GISTs that ... PDGFRA and PDGFRB). Mouse ICC precursors were retrovirally transduced to ...
PDGFRA protein expression summary - The Human Protein Atlas
... PDGFRA and PDGFRB. Phosphorylates PIK3R1, PLCG1, and PTPN11. Activation of PLCG1 leads to the production of the cellular signaling molecules diacylglycerol ...
Antiangiogenic and Antitumor Activity of a Selective PDGFR ...
PDGF growth factors and receptors are involved in both autocrine and paracrine stimulation in many tumor types, in situ and in human xenografts.
Lyn mediates FIP1L1-PDGFRA signal pathway facilitating IL
... stimulates PDGFR-induced malignant hematopoiesis [13]. Some ... ERK1 and ERK2 activation by chemotactic factors in human eosinophils ...
PDGFRB gene: MedlinePlus Genetics
The signaling pathways stimulated by the PDGFRβ protein control many important processes in the cell such as growth and division (proliferation) ...
Pdgfra marks a cellular lineage with distinct contributions to ... - eLife
... activation of a gain-of ... (2013) Progenitor cells identified by PDGFR-alpha expression in the developing and diseased human heart.
platelet derived growth factor receptor beta | Type III RTKs
The experiments measuring the ability of PDGF RTK inhibitor to inhibit PDGFR autophosphorylation were carried out in intact human cells, so it ...
Autocrine PDGFR signaling promotes mammary cancer metastasis
Undiluted EpRasXT cell–conditioned medium contained 3.7–4.9 ng/ml PDGF — known to maximally stimulate proliferation of primary human fibroblasts ...
An overview of agents and treatments for PDGFRA-mutated ...
Activation or inhibition of these pathways influences cellular proliferation, angiogenesis, and apoptosis. PDGF, platelet-derived growth factor; PDGFR, platelet ...