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Identification of Tissue of Origin and Guided Therapeutic ...


Development of Genome-Derived Tumor Type Prediction to Inform ...

... diagnosis and classification of C UP according to the tissue of origin and the shift away from empirical therapy towards tailored therapy. Expand. 68 ...

CancerTYPE ID® | Hologic

Molecular gene expression profiling to predict the tissue of origin and direct site-specific therapy in patients with carcinoma of unknown primary site: a ...

Gene Expression Profiling to Identify the Histogenetic Origin of ...

Using Gene Expression Analyses to Guide Therapy Choice: A Case History ... identify metastatic carcinoma tissue of origin. J Mol Diagn 8 ...

Integrated prediction of tissue of origin in cancers of unknown primary

The long-term goal is to use the primary site identity as an additional piece of information that will guide therapy. ... tissue identification, and to ...

Adenocarcinoma of unknown primary site - UpToDate

Molecular cancer classifier assays - MCCAs can accurately identify the tissue of origin and subsequently guide site-specific therapy in patients ...

The ESMO Tumour-Agnostic Classifier and Screener (ETAC-S)

Taxonomy for therapeutic effect of molecularly guided treatment options ... tissue of origin and molecular target. Eur J Cancer. 2023; 178 ...

Circulating tumor DNA analysis in the era of precision oncology

... guide adjuvant therapy (early detection) or detect relapse. Low ... High concordance between ctDNA analysis and tumor tissue analysis, allowing ...

Tissue of Origin Test Evaluated in Patients with Cancer of Unknown ...

Although several clinical subsets with specific treatment implications have been identified, the majority of patients receive “broad ...

Tumor Marker Tests in Common Use - NCI

Circulating tumor cells of epithelial origin (CELLSEARCH). Cancer ... How used: To guide treatment and to identify those at high risk of ...

Tissue Origin Identification for Cancer of Unknown Primary - Patrinum

... treatment, providing reference to guide therapeutic decisions to treat CUP tumors in the future. Pu, Xingxiang; Yang, Sa; Xu, Yan; Chen ...

Therapeutic Actionability of Circulating Cell-Free DNA Alterations in ...

Tissue-of-origin testing, often by microarray-based gene expression tests, as well as next-generation sequencing (NGS), has also been explored ...

Genetic Tests for Targeted Cancer Therapy - Testing.com

... tissue, reducing many of the side effects associated with standard therapy. ... These genetic tests are used to help guide treatment for ...

Circulating tumor DNA - Cancer Research and Treatment

The mutations of 13 genes were concordantly found in primary tumor tissue and plasma ctDNA, giving a detection sensitivity of 45%. ... origin, but also DNA from ...

A New Artificial Intelligence Tool for Cancer | Harvard Medical School

ChatGPT-like AI model can diagnose cancer, guide treatment choice, predict survival across multiple cancer types · Cancer detection · Predicting ...

Genomic Profiling - Oncology - Tempus

Provides accurate insight through true identification of somatic alterations and maximizes targeted therapy opportunities. ... Concurrent tissue and ...

Breast cancer - Symptoms and causes - Mayo Clinic

Breast cancer is a kind of cancer that begins as a growth of cells in the breast tissue. After skin cancer, breast cancer is the most common cancer diagnosed ...

Diagnostics in oncology - Roche

Diagnostics impact almost all key decision along the patient journey · Risk evaluation · Cancer screening · Disease determination · Therapy ...

Gene Profiling–guided Therapy May Improve Survival in Patients ...

Molecular gene-expression profiling is an emerging technique to determine tissue of origin in patients with carcinoma of unknown primary, ...

Image Guided Cancer Therapy Research (IGCTR) Program

Develop and validate novel imaging to identify and target the tumor while avoiding normal tissue. Use advanced imaging approaches to better resolve tumor and ...

Molecular and Proteomic Diagnostic Testing for Hematology and ...

• nuclear expression of AR-V7 will be assessed to guide subsequent therapeutic ... Oncology (tissue of origin), microarray gene expression profiling of > 2000.