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Improving laboratory diagnosis of von Willebrand Disease


von Willebrand disease: A guide for the internist

The diagnosis of VWD can be nuanced because the clinical bleeding symptoms can vary, and specialized laboratory tests can be difficult to ...

Towards improved diagnosis of von Willebrand disease

Clinical identification, diagnosis and sub-typing of VWD are aided by laboratory testing but remain problematic for a variety of reasons. First, ...

How is von Willebrand disease diagnosed? - Stago US

(3) BT: bleeding time (Ivy method) is only increased in around 50% of cases; it is never increased in type 2N von Willebrand disease; in vitro tests to ...

2020 Science Update on the Diagnosis of Von Willebrand Disease

Von Willebrand disease (VWD) is the most common inherited bleeding disorder and is estimated to affect up to 1% of the U.S. population.

Diagnosis and management of von Willebrand disease in Australia

Diagnosis requires evidence of personal or family history of (mainly) mucocutaneous bleeding, together with laboratory findings that demonstrate quantitative or ...

Utility of repeat testing in the evaluation for von Willebrand disease ...

The laboratory diagnosis of VWD in pediatric patients is complicated by VWF interassay and intra‐assay variability, stress‐induced elevations in VWF levels, and ...

Laboratory Tests for von Willebrand Factor (VWF) - DiaPharma

Second tier specialized testing should include multimeric analysis, the von Willebrand Factor collagen binding assay (VWF:CBA), ristocetin ...

Von Willebrand Disease - Merck Manual Professional Edition

Diagnosis requires measuring total plasma VWF antigen, VWF function as determined by the ability of plasma to support agglutination of normal platelets by ...

Von Willebrand Disease in Women | ACOG

See Figure 1 for laboratory tests for suspected bleeding disorders. If a patient's medical history is suggestive of an underlying bleeding condition, specific ...

A guide for people living with von Willebrand disorder

Specialised laboratory test results for VWD. ... The hormones can increase. VWF and factor ... The diagnosis, evaluation, and management of von Willebrand Disease.

AVWPR - Overview: von Willebrand Disease Profile, Plasma

Detection of deficiency or abnormality of von Willebrand factor (VWF) and related deficiency of factor VIII coagulant activity Subtyping von Willebrand ...

Approach to the adult with a suspected bleeding disorder - UpToDate

Outline · - VWD testing · - Platelet function testing · - Tests for defects in fibrin crosslinking or fibrinolysis · - Chromogenic factor VIII ...

Von Willebrand Panel - Health Encyclopedia

This panel of tests is used to diagnose von Willebrand disease. This is a bleeding disorder that causes excessive bleeding from minor injuries or normal ...

Von Willebrand's Disease Testing - VCA Animal Hospitals

Initial tests include an evaluation of a complete blood count (CBC) to ensure that other causes of excessive bleeding, such as reduced platelet numbers, are not ...

Test Code VON von Willebrand Factor Antigen, Plasma

The diagnosis of von Willebrand disease requires a combination of clinical and laboratory information. For a streamlined approach to testing, a panel of ...

Von Willebrand disease - Orphanet

Diagnosis relies on laboratory tests involving functional and immunological assays of VWF and FVIII levels. Determination of the type of VWD requires other ...

New advances in the diagnosis of von Willebrand disease - OUCI

Laboratory diagnosis requires at least initially a measurement of von Willebrand factor (VWF) antigen levels, VWF platelet binding activity (VWF:RCo, VWF:GPIbM, ...

von Willebrand disease, molecular biology and diagnosis - Elsevier

The VWF gene has been characterised using molecular biology techniques, which have acquired an important role in diagnosis of von Willebrand disease, as well as ...

diagnosis of von willebrand disease - WFH

In addition, it serves to rationalize laboratory bleeding investigation and evaluate the propensity of patients to bleed. Laboratory diagnosis. VWD is an ...

Advances in diagnosis of von Willebrand disease - Researcher | An Ap

Laboratory diagnosis requires a series of assays to determine VWF concentration and function, and factor VIII activity, but no single test is available to ...