- The molecular mechanisms of chemoresistance in cancers🔍
- KEGG PATHWAY Database🔍
- Engineering Cancer Cells to Short|Circuit Treatment Resistance🔍
- All Data Downloads🔍
- New tool allows researchers to study gene mutation directly within ...🔍
- European Society for Medical Oncology🔍
- Simple Blood Test Could Detect Drug Resistance in Ovarian Cancer ...🔍
- Dissecting Drivers of Therapy Resistance and Metastases in Acral ...🔍
Mapping Cancer Drug Resistance Mutations and Mechanisms
The molecular mechanisms of chemoresistance in cancers
Overcoming intrinsic and acquired drug resistance is a major challenge in treating cancer patients because chemoresistance causes recurrence, ...
07: drug structure map (no KO expansion); other: regular map (boxes linked to KOs). are used for different types of maps ...
Engineering Cancer Cells to Short-Circuit Treatment Resistance - NCI
... mechanisms—most often new genetic changes—that cancer cells acquire. This is particularly true for resistance to targeted therapies, which ...
All Data Downloads - Data | DepMap Portal
This DepMap Release contains new cell models and data from Whole Genome/Exome Sequencing (Copy Number and Mutation), RNA Sequencing (Expression and Fusions) ...
New tool allows researchers to study gene mutation directly within ...
... cancer treatments often target but frequently fail because the diseased cells mutate resistance mechanisms. ... mutation linked to treatment ...
European Society for Medical Oncology
ESMO is the European Society for Medical Oncology, providing a professional network for its members and working with national societies across Europe.
Simple Blood Test Could Detect Drug Resistance in Ovarian Cancer ...
Researchers have now discovered a way to predict which patients are likely to develop resistance to PARPi. Cancer cells with mutations in genes ...
Dissecting Drivers of Therapy Resistance and Metastases in Acral ...
This CU Cancer Center symposium was presented on 12/19/2023 by Vito W. Rebecca, PhD, an assistant professor in the Department of ...
Novel Drug Combo Is Promising for PD-L1-Resistant Solid Cancers
Combining E-602 with cemiplimab (Libtayo) established proof-of-mechanism for anti-tumor activity and tolerability in patients with ...
Genetic Mapping Study Reveals Four Key Categories of Cancer ...
A groundbreaking study using CRISPR gene editing identifies four types of cancer drug resistance mutations, offering new targets for ...
... Drug Assays Drugs Targets Documents Tissues Drug Drug Cell Mechanisms Warnings Indications Lines ... A significant effort has been made to correctly map the drug ...
Mapping the Secret Complexity of Tumors to Defeat ... - YouTube
... cancer and other highly aggressive or treatment-resistant tumors. ... ROBERT A. WEINBERG, PhD - EMT, Cancer Stem Cells and the Mechanisms ...
Researchers map paths to cancer drug resistance
The new mechanisms they identified in the laboratory were also clinically relevant, appearing in tumor cells from patients who had grown ...
Epigenetic factors can also lead to cancer. Epigenetic mechanisms. The term also refers to the mechanism of changes: functionally relevant ...
Talking Hope: How precision medicine is personalizing cancer care
A leader in precision oncology research and treatment, City of Hope's groundbreaking precision medicine program empowers patients to make the ...
New Therapies Expand Options in Recurrent Small Cell Lung Cancer
... mutations that make them resistant to their current treatments. One key mutation is called the C481S mutation, which occurs on the BTK site.
Promega Corporation is a worldwide leader in applying biochemistry and molecular biology to the development of innovative, high-value products for the life ...
Gene expression and regulation | AP®/College Biology
In this unit, we'll examine the nitty gritty of replication, transcription, and translation, and learn how seemingly small mutations can have a big impact on ...
StitchR technology delivers large genes for muscular dystrophy ...
Scientists map cancer mutations in EGFR gene, revealing drug resistance paths.
American Journal of Obstetrics & Gynecology: Home Page
Uterine cancer incidence trends and 5-year relative survival by race/ethnicity and histology among women under 50 years. Wijayabahu et al. American Journal of ...