Novel Therapeutics for Neonatal Seizures

Etiologies and Seizure Outcome of Neonatal Seizures

Due to their γ-aminobutyric acid (GABA) mechanisms, phenobarbital has been long proposed as the favorite anti-seizure medication in treating neonatal seizures.

Novel drugs and early polypharmacotherapy in status epilepticus

These changes tend to promote self-sustaining seizures. Current SE guidelines recommend a rapid stepwise treatment using benzodiazepines in ...

Benign Neonatal Convulsions Treatment & Management

Continuing antiepileptic treatment for more than 10 days may not be necessary in benign idiopathic neonatal convulsions. Keep in mind that ...

Epileptic Disorders - A novel mutation in KCNQ3-related benign ...

A novel mutation in KCNQ3-related benign familial neonatal epilepsy: electroclinical features and neurodevelopmental outcome Volume 21, issue 1, February 2019.

Genetic testing for neonatal seizures - VJNeurology

Elissa Yozawitz, MD, FAES, Montefiore Medical Center/Albert Einstein College of Medicine, Bronx, NY, discusses clinical signs that suggest a ...

Medline ® Abstract for Reference 130 of 'Clinical features, diagnosis ...

... seizures in neonatal hypoxic-ischemic encephalopathy. METHODS This study included infants undergoing therapeutic hypothermia at St. Louis Children's ...

EEG background activity, seizure burden and early childhood ...

Effective targeting of anti-seizure medications using clinical manifestations alone is challenging. However, there is a lack of newborn EEG data from sub- ...

Updated guidelines for the classification of neonatal epilepsy ...

Elissa Yozawitz, MD, FAES, Montefiore Medical Center/Albert Einstein College of Medicine, Bronx, NY, speaks on the updated International ...

ClinicalKey - Lead with Answers

Search for conditions, treatments, drugs, books, journals, and more · Inform your clinical decisions · Deepen your specialty and medical knowledge · Get news and ...

Evaluating newer medications in the treatment of neonatal seizures

Historically, treatments for neonatal seizures have involved phenobarbital, a drug with side effects including sedation and respiratory ...

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Lacosamide Pharmacokinetics and Retention in Japanese Patients ...

Lacosamide (LCM), a third-generation antiseizure medication (ASM), is widely used as a monotherapy and adjunctive treatment for focal and ...

Caffeine - Uses, Side Effects, and More - WebMD

... seizures in some people. ... Aranda, J. V., Gorman, W., Bergsteinsson, H., and Gunn, T. Efficacy of caffeine in treatment of apnea in the low-birth-weight infant.

Pethidine - Wikipedia

Pethidine, also known as meperidine and sold under the brand name Demerol among others, is a fully synthetic opioid · Pethidine is indicated for the treatment of ...

Zellweger syndrome - Wikipedia

Newborns may present with profound hypotonia (low muscle tone), seizures, apnea, and an inability to eat. ... "Identification of novel mutations in PEX2 ...

Jundishapur Journal of Natural Pharmaceutical Products، Volume ...

Cancer is a global health burden, and the discovery of novel therapeutic agents remains a critical pursuit. Marine organisms, including sponges, have ...

Iranian Journal of Pediatrics، Volume:34 Issue: 6, Dec 2024 - Magiran

... children following conservative treatment. Results. After 2 years of ... neonatal convulsions. Focal infarction/hemorrhage was most often associated ...

Guidelines on Neonatal Seizures - World Health Organization (WHO)

In particular, rather few studies address issues related to the use of antiepileptic drugs (AEDs), such as indications for acute therapy, selection of ...

Rrt Clinical Simulation Practice

Neonatal and Pediatric Respiratory Care Julianne Perretta,2014-05-14 ... Novel•Ties A Study Guide This reproducible study guide to use in conjunction ...

Neonatal Seizure Disorders - Merck Manual Professional Edition

When neonatal hypoxia is treated with therapeutic hypothermia (usually whole-body cooling), seizures may be less severe but may recur during rewarming. Ischemic ...