Overcoming Resistance to Temozolomide in Glioblastoma

Mechanism of Treatment Resistance in Human Glioblastoma

W.K. Alfred Yung, M.D. Professor, Department of Neuro-Oncology, Division of Cancer Medicine; Senior Advisor, Brain Tumor Center; ...

IRP1 mediated ferroptosis reverses temozolomide resistance in ...

The prognosis of glioblastoma (GBM) patients is poor, and temozolomide (TMZ) resistance has become an important obstacle to its treatment ...

Alkylpurine–DNA–N-glycosylase confers resistance to ... - JCI

Glioblastoma multiforme (GBM) is the most common and lethal of all gliomas. The current standard of care includes surgery followed by ...

How Have Your Glioblastoma Experiences With Temozolomide Been?

... treatment of patients with malignant glioma. A biopsy reveals whether the ... Resistance to alkylating agents via direct DNA repair by O6-methylguanine...

Sequential bortezomib and temozolomide in recurrent glioblastoma

The trial aimed to identify mechanisms underlying objective responses. The treatment was safe, and interim analysis confirms clinical ...

Dr. Toms on NovoTTF and Temozolomide for Glioblastoma - YouTube

Steven A. Toms, MD, director, neurosurgery, Geisinger Health System, discusses the combination of the Novo Tumor Treating Fields (NovoTTF) ...

Targeting Cancer Stem Cells for Treatment of Glioblastoma - YouTube

Targeting Cancer Stem Cells for Treatment of Glioblastoma - Parvinder Hothi, Ph.D. The Seattle Science Foundation is a not for profit ...

Brain cancer patients provided new hope with altering drug dosage

... treatment with the drug Temodal (TMZ) is a valuable therapeutic option for patients with recurrent glioblastoma multiforme (GBM)," says Dr ...

Dr. Mrugala on Extending Treatment With Temozolomide ... - YouTube

Dr. Mrugala on Extending Treatment With Temozolomide in Newly Diagnosed Glioblastoma. 1K views · 8 years ago ...more. OncLive. 23.8K.

FDA approves new and updated indications for temozolomide

... treatment of adults with newly diagnosed glioblastoma, concomitantly with radiotherapy and then as maintenance treatment. Additional ...