RNA and neuronal function

A Comprehensive Binding and Functional Map of Human RNA ...

Brenton Graveley, Ph.D., University of Connecticut Health Center, studies RNA binding proteins (RBPs) with a focus on understanding their ...

Netrin1 plays unexpected role in spinal cord development | UCLA

“The regional specificity of signaling molecules like BMP and netrin1 is extremely important for proper neural network formation and function,” ...

Enabling Technologies for Revealing Druggable Paths in RNA Biology

Since that time, RNA has been shown to significantly impact nearly all of human biology from transcriptional regulation to splicing, translation ...

Neuron-specific gene family member 1 is a potential new ...

Neuron-specific gene family member 1 can play a complex biological function ... The single-cell RNA-seq dataset GSE176078 of BC was obtained from ...

Conferences & training - EMBO

RNA-protein complexes: from molecular assembly to physiological functions and disease ... Computational approaches to neuronal and behavioural data analysis.

Promega Corporation

The SV Total RNA Isolation System was used to isolate high-quality RNA ... This process supports neuronal function, particularly through metabolic crosstalk ...

University of Manitoba - Faculty of Medicine - Xie lab homepage

Other exons studied include those involved in neuronal function, human genetic disease or cell growth/apoptosis, or splicing regulations involving other ...

ISH Data :: Allen Brain Atlas: Mouse Brain

A genome-wide, high-resolution atlas of gene expression throughout the adult mouse brain. Key features:

Exercise helps neurons to grow, study - Tech Explorist

This research could pave the way for new therapies to repair nerve damage and improve motor function. ... RNA, and proteins that could promote ...

Scientists discover 'entirely unanticipated' role of protein netrin1 in ...

For these sensory processes to function, specific neurons must form in carefully defined regions. ... RNA translation. "Netrin1 is the most ...

Mitochondrial pyruvate transport regulates presynaptic metabolism ...

... neuronal functions and the molecular mechanisms of pyruvate oxidation in neurons ... Depletion of neuronal MPC1 with short hairpin RNA (shRNA) ( ...

Exercise promotes nerve growth at the cellular level - News-Medical

"Exercise seems to impact not just neuron growth but also how mature and well-functioning they are." The results suggest that biochemical ...

TAR DNA-binding protein 43 - Wikipedia

"Identification of neuronal RNA targets of TDP-43-containing ribonucleoprotein complexes". ... "Characterization and functional implications of the RNA ...

Hypothesis

The authors profile NRL's protein interactome, revealing several RNA-binding proteins (RBPs) among its components. ... neuronal function factors. While the ...

Trace Neuroscience Launches with $101M and a Potential Genomic ...

“UNC13A is critical for neurons to communicate amongst each other and with muscles through synaptic function, which is lost in ALS. Being able ...

Trace Neuroscience Launches With $101 Million Series A Financing ...

“UNC13A is critical for neurons to communicate amongst each other and with muscles through synaptic function, which is lost in ALS. Being able ...

Exercise Spurs Nerve Growth Through Biochemical and Physical ...

Interestingly, axonogenesis is similarly upregulated in both mechanically and biochemically stimulated motor neurons, but RNA sequencing reveals ...

Uncovering Gene Function in Human Neurons Using CRISPR

... neurons. This platform enables systematic elucidation of gene function in human neurons and reveals neuron-specific roles of genes for ...

When muscles work out, they help neurons grow - Medical Xpress

... RNA, and a mix of other proteins. "I would ... Gene named for mythical Irish land could aid muscle function after traumatic nerve injuries.

How to accelerate glycolysis and treat Parkinson's disease

A close-up of a synapse where two neurons exchange molecules. There are astrocytes ...