Role of Endoplasmic Reticulum Stress Sensor IRE1α in Cellular ...
The UPRosome – decoding novel biological outputs of IRE1α function
The UPR consists of three arms and the most conserved branch is initiated by the stress sensor inositol-requiring enzyme 1α (IRE1α; also known ...
Endoplasmic Reticulum Stress in Disease Pathogenesis
Mammalian cells have evolved an intricate set of signaling pathways from the ER to the cytosol and nucleus, to allow the cell to respond to the ...
Role for Endoplasmic Reticulum Stress in Diabetes Mellitus
IRE1α activates XBP1 by its alternative splicing. XBP1s is a transcriptional transactivator of genes regulating protein maturation, folding, and export from the ...
Specifically, it protects dopamine neurons from endoplasmic reticulum (ER) stress-induced death. It exerts this action by binding to ERN1, the unfolded protein ...
SEC63 - Wikipedia, la enciclopedia libre
... sensor IRE1α, que se encarga de reconocer los niveles de estrés de la ... endoplasmic reticulum stress». Journal of Experimental & Clinical Cancer ...