Shaping DNA damage responses

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Cell response to ... et al. Metabolically inducing defects in DNA repair sensitizes BRCA–wild-type cancer cells to replication stress.

A non-canonical role of somatic Cyclin D/CYD-1 in oogenesis and in ...

The quality was categorized as normal, or mild or severe based on its morphology (cavities, shape, organization) as shown in S1G Fig. ... DNA damage response (DDR) ...

Research claims cannabis use can cause chromosomal damage ...

The paper describes cannabis as a "genotoxic" substance because it damages a cell's genetic information, which can lead to DNA mutations, ...

What Are Platelets? Function & Anatomy - Cleveland Clinic

Their primary job is to stop the bleeding if you're injured. If a blood vessel is damaged, platelets cluster together to form a plug first and then a clot to ...

Teeny tardigrades can survive space and lethal radiation. Scientists ...

The findings point to a complex defense system that shields tardigrade DNA from radiation-induced damage and can pave the way for devising ...

Living microbes discovered in Earth's driest desert - ScienceDaily

A new technique allows researchers to separate external and internal DNA to identify microbes colonizing the hostile environment of the ...

Understanding the Crucial Role of Phosphate and Iron Availability in ...

Finally, we discuss how the transcription factor phosphate starvation response might be a crucial genetic element to integrate the plant's needs of nitrogen, ...

Evo—an AI-based model for deciphering and designing genetic ...

For this new study, the researchers trained a computer with DNA data, which then applied it to create something new. The model, Evo, can not ...

DNA Damage Response (DDR) Pathway - Sigma-Aldrich

Targeting the DNA damage response pathway is important in research on cancer, cell signaling, neurological disease, and more. See how key targets of DNA damage, ...

Study identifies a potential treatment for Sandhoff and Tay-Sachs ...

The opinions expressed here are the views of the writer and do not necessarily reflect the views and opinions of News Medical. Cancel reply to ...

Brain Autopsies Reveal a Potential New Culprit Behind Alzheimer's

In response to infection or to clear out dead cells, these nifty shape ... damage brain cells and possibly contribute to the progression of ...

Biotechnology of Promising Genes from Extremophiles to Produce ...

... respond to challenging circumstances. ... This resistance is due to its incredible ability to repair DNA damage and have four to ten copies of the ...

Cancer biologists discover a new mechanism for an old drug ...

Some DNA damaging drugs send a signal to the cell to stop making new ... Reference: Chen, Jung-Kuei et al., An RNA damage response ...

Scientists gain new insights into how mass is distributed in hadrons

This is similar to how researchers used X-ray diffraction to discover the iconic double-helix shape of DNA. Theoretical calculations help ...

Meet Evo, the DNA-trained AI That Creates Genomes From Scratch

... DNA on Earth? That future just got a bit ... DNA, and until we see that DNA come alive. Very cool accomplishment, lots of steps to go. Reply ...

DNA Damage Response - AstraZeneca

To repair these DNA damage events and enable cells to function normally, a series of processes takes place, collectively known as the DNA Damage Response (DDR).

DNA Damage Repair Pathways - Cell Signaling Technology

Cells undergo a constant barrage of exogenous and endogenous stressors that can cause DNA damage triggering a DNA-damage response (DDR), activating a number ...

QuickGO::Term GO:0006974

GO:0006974 JSON · DNA damage response · Synonyms · Ancestor Chart · Child Terms · Annotation Blacklist · Cross-references · Replaces · Co-occurring Terms.