Trabectedin and lurbinectedin

A New Treatment Option for Relapsed/Refractory Small-Cell Lung ...

The antitumor drugs trabectedin and lurbinectedin induce transcription-dependent replication stress and genome instability. Mol Cancer Res. 2018;17:773-782 ...

Lurbinectedin - Wikipedia

Lurbinectedin, sold under the brand name Zepzelca, is a medication used for the treatment of small cell lung cancer.

Specific Effects of Trabectedin and Lurbinectedin on ... - Sigma-Aldrich

Specific Effects of Trabectedin and Lurbinectedin on Human Macrophage Function and Fate-Novel Insights. by Adrián Povo-Retana, Marina Mojena, ...

relevance for their anti-tumor activity - Altmetric

Immunometabolic actions of trabectedin and lurbinectedin on human macrophages: relevance for their anti-tumor activity · Frontiers in immunology, August 2023.

FDA grants accelerated approval to lurbinectedin for metastatic small

The Food and Drug Administration granted accelerated approval to lurbinectedin(ZEPZELCA, Pharma Mar SA) for adult patients with metastatic small cell lung ...

Quick Take: Doxorubicin plus Trabectedin in Leiomyosarcoma

... trabectedin followed by trabectedin maintenance therapy, as compared with doxorubicin monotherapy, in these patients. In this phase 3 ...

Lurbinectedin in combination with pembrolizumab in relapsed SCLC

safety of combining lurbinectedin with pembrolizumab in the second-line treatment of recurrent small cell lung cancer. The combination ...

Trabectedin or Dacarbazine for Treatment of Patients ... - YouTube

George D. Demetri, MD, director, Center for Sarcoma and Bone Oncology, Dana-Farber Cancer Institute, discusses the trial the led to the ...

Palliative radiotherapy with lurbinectedin in patients with extensive ...

Lurbinectedin recently gained accelerated approval following the demonstration of a favorable response rate, duration of response, ...