A cell|based model system links chromothripsis with hyperploidy

A cell‐based model system links chromothripsis with hyperploidy

Our in vitro system uncovered a propensity of chromothripsis to occur in cells with damaged telomeres, and in particular in hyperploid cells. Analysis of ...

A cell-based model system links chromothripsis with hyperploidy

A remarkable observation emerging from recent cancer genome analyses is the identification of chromothripsis as a one-off genomic ...

A cell-based model system links chromothripsis with hyperploidy

Our in vitro system uncovered a propensity of chromothripsis to occur in cells with damaged telomeres, and in particular in hyperploid cells.

Cell‐based model systems for genome instability: Dissecting the ...

Chromothripsis, originally discovered in cancer genomes, constitutes a new class of massive genomic rearrangements, which is characterized by ...

Chromothripsis in cancer | Nature Reviews Cancer

A cell-based model system links chromothripsis with hyperploidy. Mol. Syst. Biol. 11, 828 (2015). Article PubMed PubMed Central Google ...

Chromothripsis: an emerging crossroad from aberrant mitosis to ...

S.M.. et al. (. 2015. ). A cell-based model system links chromothripsis with hyperploidy . Mol. Syst. Biol. 11. ,. 828 . Google Scholar · Crossref · Search ADS.

Chromothripsis, DNA repair and checkpoints defects - ScienceDirect

... chromothripsis in medulloblastoma suggests that chromothripsis scoring ... A cell-based model system links chromothripsis with hyperploidy. Mol. Syst ...

Emerging Mechanisms of Chromothripsis: Trends in Cell Biology

A renewed model of pancreatic cancer evolution based ... 31. Mardin, B.R. ... A cell-based model system links chromothripsis with hyperploidy.

Micronuclei-based model system reveals functional consequences ...

(2015) A cell-based model system links chromothripsis with hyperploidy. Molecular Systems Biology 11:828. https://doi.org/10.15252/msb ...

Cell‐based model systems for genome instability: Dissecting the ...

Chromothripsis is a form of genomic instability that was shown to play a major role in cancer. Beyond cancer, this type of catastrophic ...

Comprehensive analysis of chromothripsis in 2,658 human cancers ...

A cell-based model system links chromothripsis with hyperploidy. Mol. Syst. Biol. 11, 828 (2015). Article PubMed PubMed Central Google ...

CTLPScanner: a web server for chromothripsis-like pattern detection

M. et al. A cell-based model system links chromothripsis with hyperploidy. Mol. Syst. Biol. 2015. 11.

Mutational game changer: Chromothripsis and its emerging ...

... of cell death upon DNA damage, resulting in cell survival. Chromothripsis ... A cell-based model system links chromothripsis with hyperploidy. Mol. Syst ...

Chromothripsis—Explosion in Genetic Science - MDPI

... connection between chromothripsis and cell hyperploidization. Moreover ... A cell-based model system links chromothripsis with hyperploidy. Mol. Syst ...

On the Complexity of Mechanisms and Consequences of ... - Frontiers

A cell-based model system links chromothripsis with hyperploidy. Mol. Syst. Biol. 11:828. doi: 10.15252/msb.20156505. PubMed Abstract | CrossRef Full Text ...

Comprehensive analysis of chromothripsis in 2,658 human cancers ...

A renewed model of pancreatic cancer evolution based on ... A cell-based model system links chromothripsis with hyperploidy. Mol ...

Chromothripsis and Kataegis Induced by Telomere Crisis - Cell Press

35. Mardin, B.R. ∙ Drainas, A.P. ∙ Waszak, S.M. ... A cell-based model system links chromothripsis with hyperploidy. Mol. Syst. Biol. 2015 ...

Chromoanagenesis: cataclysms behind complex chromosomal ...

... based models have the potential to explain many features of chromothripsis ... A cell-based model system links chromothripsis with hyperploidy.

Chromosomal Rearrangements and Chromothripsis: The Alternative ...

A cell-based model system links chromothripsis with hyperploidy. Mol. Syst. Biol. 2015, 11, 828. [Google Scholar] [CrossRef] [PubMed]; Maher ...

Chromothripsis in Human Breast Cancer - AACR Journals

In breast cancer, chromothripsis studies based on whole-genome sequencing data are rare. ... A cell-based model system links chromothripsis with hyperploidy . Mol ...