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Boronophenylalanine


4-Borono-L-phenylalanine | C9H12BNO4 | CID 150315 - PubChem

4-boronophenylalanine; 4-boronophenylalanine hydrochloride; 4-boronophenylalanine hydrochloride, (10)B; 4-boronophenylalanine, (10)B; L-(10)BPA ...

4 Boronophenylalanine - an overview | ScienceDirect Topics

Boron neutron capture therapy (BNCT) depends upon the accumulation and retention of boron-10 in brain tumor cells and not in normal brain cells.

Boronophenylalanine, a boron delivery agent for boron ... - PubMed

The efficacy of boron neutron capture therapy relies on the selective delivery of boron carriers to malignant cells. p-Boronophenylalanine (BPA), a boron ...

4 Boronophenylalanine - an overview | ScienceDirect Topics

Some promising boron compounds, such as BSH and BPA, can penetrate the BBB and localize in tumor cells when administered intravenously or intracarotidly.

Evaluation of Pharmacokinetics of Boronophenylalanine and Its ...

This study evaluated the pharmacokinetics and safety of 10 B-labeled BPA ( 10 B-BPA, abbreviated as BPA) and its uptakes in gastric cancer.

Definition of boronophenylalanine-fructose complex - NCI Dictionary ...

NCI's Dictionary of Cancer Terms provides easy-to-understand definitions for words and phrases related to cancer and medicine.

5-Aminolevulinic acid increases boronophenylalanine uptake into ...

Boron neutron capture therapy (BNCT) is a high-LET particle radiotherapy clinically tested for treating malignant gliomas.

Poly(vinyl alcohol) boosting therapeutic potential of p ... - Science

In the current clinical boron neutron capture therapy (BNCT), p-boronophenylalanine (BPA) has been the most powerful drug owing to its ...

Selective Targeting of Boronophenylalanine to Melanoma in BALB/c ...

The concentrations of boron achieved in tumor ranged from 9–33 µg/g, and are within the range estimated to be necessary for successful application of the ...

p-Boronophenylalanine: Uses, Interactions, Mechanism of Action

p-Boronophenylalanine is under investigation in clinical trial NCT00039572 (Boron Neutron Capture Therapy in Treating Patients With ...

Analyzing spatial distribution between 18 F-fluorodeoxyglucose and ...

Para-boronophenylalanine (BPA) agent, specific for the L-type amino acid transporter 1 (LAT1) expressed in tumors, can selectively uptake the ...

L-p-Boronophenylalanine | Biochemical Reagent | MedChemExpress

Lp-Boronophenylalanine (S)-2-Amino-3-(4-boronophenyl)propanoic acid is a biochemical reagent that can be used as a biological material or organic compound

Boronophenylalanine, a boron delivery agent for boron neutron ...

Abstract. The efficacy of boron neutron capture therapy relies on the selective delivery of boron carriers to malignant cells. p- ...

L-4-Boronophenylalanine (all around the one molecule) - Arkivoc

In this review, various aspects of the chemistry of 4-boronophenylalanine will be considered, including methods of its synthesis, drug formulation, ...

Hydroxylforms of p-Boronophenylalanine as Potential Boron ...

Abstract. Hydroxylforms of boronophenylalanine (BPA) were synthesized by conjugation with a cascade of polyols to decrease the BPA uptake of normal.

Boron neutron capture therapy of anterior chamber melanoma with p ...

Phenylalanine is an amino acid precursor of melanin and when boronated (p-boronophenylalanine [BPA]) was found to be selectively taken up by Greene melanoma ...

Borofalan (CAS 80994-59-8) - Cayman Chemical

Borofalan: A radiation sensitizer. CAS Number: 80994-59-8. Synonyms: Boronophenylalanine B-10, 10B-L-BPA. Purity: ≥95%.

Boronophenylalanine, a boron delivery agent for ... - ResearchGate

... Presently, there are two boron compounds that are used clinically: p-boronophenylalanine (BPA) and sodium borocaptate (BSH). BPA is a phenylalanine ...

boronophenylalanine | C9H12BNO4 - ChemSpider

ChemSpider record containing structure, synonyms, properties, vendors and database links for boronophenylalanine, 90580-64-6.

Boronophenylalanine B-10 HCl | BPA | BNCT | CAS#74611-70-4

Boronophenylalanine B-10 (also known as BPA), a boron delivery agent, is used in boron-neutron capture therapy (BNCT) for metastatic melanomas and other tumors.