Characteristics and Biomarkers of Ferroptosis

Characteristics and Biomarkers of Ferroptosis - Frontiers

Ferroptosis is a non-apoptotic and oxidative damage-related RCD (Dixon et al., 2012), mainly driven by iron accumulation, lipid peroxidation, and subsequent ...

Characteristics and Biomarkers of Ferroptosis - PubMed

In this mini-review, we not only summarize the latest knowledge about the characteristics of ferroptosis in vitro and in vivo, but also discuss the specificity ...

Characteristics and Biomarkers of Ferroptosis - PMC - PubMed Central

Ferroptosis appears to be the main cause of tissue damage driven by iron overload and lipid peroxidation.

Identification of ferroptosis related biomarkers and immune ...

Characteristics of ferroptosis, such as iron accumulation ... Identification of ferroptosis related biomarkers and immune infiltration ...

Analysis and identification of oxidative stress-ferroptosis related ...

In this study, four biomarkers, CDKN1A, GPX4, PRDX1, and PRDX6, were used to diagnose stroke and assess the treatment effects. Previous research ...

Ferroptosis - an overview | ScienceDirect Topics

It is characterized by an overwhelming, iron-dependent accumulation of lethal lipids and reactive oxygen species (ROS) [2]. In ferroptotic cells, the ...

(PDF) Characteristics and Biomarkers of Ferroptosis - ResearchGate

Hallmarks of ferroptosis. Ferroptosis is a type of iron-dependent regulated cell death mainly caused by unrestricted lipid peroxidation and subsequent membrane ...

The therapeutic and biomarker significance of ferroptosis in chronic ...

In the context of tumors, ferroptosis is closely associated with the biological characteristics of tumor cells. The hypoxic microenvironment ...

Programming a Ferroptosis‐to‐Apoptosis Transition Landscape ...

Ferroptosis is driven by iron-dependent lipid peroxidation and currently has no characteristic biomarkers or gene signatures. Here a ...

Identification of Ferroptosis-related potential biomarkers and ...

A new type of iron-mediated cell death is Ferroptosis, which is characterized by the accumulation of lethal iron ions and lipid peroxidation ...

Ferroptosis: molecular mechanisms and health implications - Nature

Ferroptosis is a ROS-dependent form of cell death associated with two main biochemical characteristics, namely iron accumulation and lipid ...

Ferroptosis turns 10: Emerging mechanisms, physiological functions ...

Indeed, NADPH was found to be a biomarker predicting resistance to ferroptosis across the NCI60 set of cancer cell lines (Shimada et al., 2016a) ...

Characteristics and Biomarkers of Ferroptosis - Semantic Scholar

This mini-review not only summarizes the latest knowledge about the characteristics of ferroptosis in vitro and in vivo, but also discusses ...

Abnormal Levels of Serum Ferroptosis‐Related Biomarkers in ...

This study aimed to measure the concentrations of ferroptosis-related biomarkers, namely, iron (Fe), lipid peroxide (LPO), reactive oxygen ...

Ferroptosis Biomarkers for Predicting Prognosis and Immunotherapy ...

Our study demonstrated that ferroptosis was significantly associated with prognosis, clinical characteristics, immune-checkpoint gene expression, and tumor ...

Predictive value of ferroptosis-related biomarkers for diabetic kidney ...

Receiver operating characteristics (ROC) curves were drawn using GraphPad Prism 9 (GraphPad Software Inc., San Diego, CA, USA), and the area ...

Characteristics and Biomarkers of Ferroptosis - Altmetric

Characteristics and Biomarkers of Ferroptosis. Overview of attention for article published in Frontiers in Cell and Developmental Biology, January 2021.

Novel diagnostic biomarkers of oxidative stress, ferroptosis, immune ...

In order to further explore the specific protective mechanism of PTGS2 knockdown in the progression of IS, we detected the levels of MDA, ROS, GSH and OSI in ...

Molecular Mechanisms of Ferroptosis and Relevance to ... - MDPI

The overexpression of some genes/proteins that are involved in lipid metabolism have been used as biomarkers of ferroptosis. These include (1) ...

Mechanisms and pharmacological applications of ferroptosis

formally named this form of iron-dependent cell death as 'ferroptosis' (5). Ferroptosis differs from necrosis, apoptosis, and autophagy in both morphological ...