Chromothripsis is a common mechanism driving ...

Chromothripsis is a common mechanism driving ... - Genome Biology

Local chromosome shattering, termed chromothripsis, is a mechanism proposed to be the cause of clustered chromosomal rearrangements and was ...

Chromothripsis is a common mechanism driving genomic ... - PubMed

We conclude that chromothripsis is a prevalent mechanism driving structural rearrangements in colorectal cancer and show that a complex ...

Chromothripsis is a common mechanism driving genomic ...

Local chromosome shattering, termed chromothripsis, is a mechanism proposed to be the cause of clustered chromosomal rearrangements and was recently described ...

geno-05 chromothripsis is a common mechanism driving genomic ...

Findings based on recent advances in next-generation sequence analysis suggest that, in some tumors, a single catastrophic event, termed chromothripsis, results ...

Chromothripsis is a common mechanism driving genomic ...

Chromothripsis is a common mechanism driving genomic rearrangements in primary and metastatic colorectal cancer · Abstract · Keywords · UN SDGs · Access to Document.

Chromothripsis as a mechanism driving complex de novo structural ...

The pattern of random joining of chromosomal fragments that we observe here strongly resembles the somatic rearrangement patterns—termed chromothripsis—that ...

(PDF) Chromothripsis is a common mechanism driving genomic ...

We conclude that chromothripsis is a prevalent mechanism driving structural rearrangements in colorectal cancer and show that a complex interplay between point ...

Comprehensive analysis of chromothripsis in 2,658 human cancers ...

Recent studies in selected cancer types have suggested that chromothripsis may be more common ... Chromothripsis as a mechanism driving complex de ...

Chromothripsis is a common mechanism driving genomic ... - Gale

... common mechanism driving ... Chromothripsis is a common mechanism driving genomic rearrangements in primary and metastatic colorectal cancer ...

Chromothripsis - an overview | ScienceDirect Topics

Chromothripsis may drive cancer development through a variety of oncogenic lesions such as formation of fusion genes, disruption of tumor suppressors or ...

Chromothripsis: Current Biology - Cell Press

This generates a highly rearranged chromosome from a single catastrophic event (Figure 1). Previous complex chromosome rearrangements could be ...

Chromothripsis is a common mechanism driving genomic ...

Dive into the research topics of 'Chromothripsis is a common mechanism driving genomic rearrangements in primary and metastatic colorectal cancer'. Together ...

Chromothripsis, DNA repair and checkpoints defects - ScienceDirect

Chromoanasynthesis is triggered by cellular stress and occurs through replication-based mechanisms such as Fork-Stalling and Template Switching (FoSTes) [12] ...

Chromothripsis in Chronic Lymphocytic Leukemia: A Driving Force ...

Chromothripsis represents a mechanism ... Chromothripsis Is a Common Mechanism Driving Genomic Rearrangements in Primary and Metastatic Colorectal Cancer.

Chromothripsis in cancer | Nature Reviews Cancer

a, A lagging mitotic chromosome results in the formation of a micronucleus, which can undergo chromothripsis via two potential mechanisms.

Chromothripsis is a common mechanism driving genomic ... - Ex Libris

Chromothripsis is a common mechanism driving genomic rearrangements in primary and metastatic colorectal cancer.-article.

On the Complexity of Mechanisms and Consequences of ... - Frontiers

In the present review, we focus on the phenomenon of chromothripsis, a new type of complex chromosomal rearrangements.

Insight into the Molecular Basis Underlying Chromothripsis - MDPI

Molecular mechanisms that underlie this phenomenon are mostly related to chromosomal sequestration throughout the micronuclei formation process. Chromothripsis ...

Chromothripsis-like patterns are recurring but heterogeneously ...

... Chromothripsis is a common mechanism driving genomic rearrangements in primary and metastatic colorectal cancer. Genome Biol. 2011, 12 (10): ...

Chromothripsis in myeloid malignancies | Annals of Hematology

Chromothripsis is thus one of the most common mechanisms involved in cancer development. The analysis of thousands of tumor samples has revealed ...