• Does Chromothripsis Make Mesothelioma an Immunogenic Cancer?🔍
• Chromothripsis🔍
• CRISPR|Cas9 Genome Editing Can Lead to Extensive ...🔍
• John Maciejowski🔍

Does Chromothripsis Make Mesothelioma an Immunogenic Cancer?

In summary, the most recent literature suggests that in contrast to hypotheses based on NGS studies, MM may be an immunogenic tumor, an interpretation that is.

Chromothripsis: a new molecular mechanism in cancer development

Indeed, in the Stephen et al. study, although chromothripsis was observed in up to ~25% of primary bone cancers, its detection frequency in many other cancer ...

CRISPR-Cas9 Genome Editing Can Lead to Extensive ...

A study showed that chromothripsis, a mutational process ... They further noted that while chromothripsis is implicated in tumorigenesis ...

John Maciejowski: Publications | Sloan Kettering Institute

APOBEC3-dependent kataegis and TREX1-driven chromothripsis during telomere crisis. ... Research programs · Research labs · Core facilities & resources.